儿童的共情与静息状态功能连通性

Q4 Neuroscience
Katherine O. Bray , Elena Pozzi , Nandita Vijayakumar , Sally Richmond , Marc Seal , Christos Pantelis , Vicki Anderson , Sarah Whittle
{"title":"儿童的共情与静息状态功能连通性","authors":"Katherine O. Bray ,&nbsp;Elena Pozzi ,&nbsp;Nandita Vijayakumar ,&nbsp;Sally Richmond ,&nbsp;Marc Seal ,&nbsp;Christos Pantelis ,&nbsp;Vicki Anderson ,&nbsp;Sarah Whittle","doi":"10.1016/j.ynirp.2022.100142","DOIUrl":null,"url":null,"abstract":"<div><p>Empathy, which is important for social functioning and mental health, is recognized to have both cognitive and affective components. While several studies have demonstrated unique neural underpinnings of empathy components in adults, few have investigated this in young people. Investigating associations between empathy and brain functional connectivity during childhood is beneficial to begin to build a comprehensive picture of the neural correlates of empathy across the lifespan. One hundred and twelve children (52% female, mean age 10 years) underwent magnetic resonance imaging brain scans including a resting-state sequence and completed empathy self-report measures. Seed-to-whole-brain resting-state functional connectivity analyses demonstrated that higher affective empathy (affective sharing and empathic distress) was associated with weaker connectivity between key hubs of the default mode network (DMN) and other widespread areas in the brain. Analyses of resting-state networks demonstrated that higher cognitive empathy was associated with both stronger and weaker connectivity between dorsal and lateral regions of the DMN and regions outside of the DMN, including the pre- and postcentral gyrus, and the cerebellum. Higher affective sharing was associated with greater connectivity between the anterior salience network and the pre- and postcentral gyrus. However, these associations did not withstand correction for multiple models. While interpretations should be made cautiously, findings suggest wide-ranging and diffuse connectivity patterns may be related to several components of empathy in children. These findings could indicate a more complex picture of the neural correlates of empathy processes in childhood, with less specialization and more widespread involvement of regions and networks. Future studies should attempt to replicate these findings using different measurement approaches.</p></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"2 4","pages":"Article 100142"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666956022000666/pdfft?md5=2ca13d9f282b344be554c373ed87d17d&pid=1-s2.0-S2666956022000666-main.pdf","citationCount":"1","resultStr":"{\"title\":\"Empathy and resting-state functional connectivity in children\",\"authors\":\"Katherine O. Bray ,&nbsp;Elena Pozzi ,&nbsp;Nandita Vijayakumar ,&nbsp;Sally Richmond ,&nbsp;Marc Seal ,&nbsp;Christos Pantelis ,&nbsp;Vicki Anderson ,&nbsp;Sarah Whittle\",\"doi\":\"10.1016/j.ynirp.2022.100142\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Empathy, which is important for social functioning and mental health, is recognized to have both cognitive and affective components. While several studies have demonstrated unique neural underpinnings of empathy components in adults, few have investigated this in young people. Investigating associations between empathy and brain functional connectivity during childhood is beneficial to begin to build a comprehensive picture of the neural correlates of empathy across the lifespan. One hundred and twelve children (52% female, mean age 10 years) underwent magnetic resonance imaging brain scans including a resting-state sequence and completed empathy self-report measures. Seed-to-whole-brain resting-state functional connectivity analyses demonstrated that higher affective empathy (affective sharing and empathic distress) was associated with weaker connectivity between key hubs of the default mode network (DMN) and other widespread areas in the brain. Analyses of resting-state networks demonstrated that higher cognitive empathy was associated with both stronger and weaker connectivity between dorsal and lateral regions of the DMN and regions outside of the DMN, including the pre- and postcentral gyrus, and the cerebellum. Higher affective sharing was associated with greater connectivity between the anterior salience network and the pre- and postcentral gyrus. However, these associations did not withstand correction for multiple models. While interpretations should be made cautiously, findings suggest wide-ranging and diffuse connectivity patterns may be related to several components of empathy in children. These findings could indicate a more complex picture of the neural correlates of empathy processes in childhood, with less specialization and more widespread involvement of regions and networks. Future studies should attempt to replicate these findings using different measurement approaches.</p></div>\",\"PeriodicalId\":74277,\"journal\":{\"name\":\"Neuroimage. Reports\",\"volume\":\"2 4\",\"pages\":\"Article 100142\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2666956022000666/pdfft?md5=2ca13d9f282b344be554c373ed87d17d&pid=1-s2.0-S2666956022000666-main.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuroimage. Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666956022000666\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Neuroscience\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroimage. Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666956022000666","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Neuroscience","Score":null,"Total":0}
引用次数: 1

摘要

共情对社会功能和心理健康至关重要,它被认为同时包含认知和情感两部分。虽然有几项研究表明,成年人的移情成分具有独特的神经基础,但很少有人研究年轻人的移情成分。研究儿童时期共情与脑功能连通性之间的关系,有助于在整个生命周期中开始建立一个全面的共情神经相关图景。112名儿童(52%为女性,平均年龄10岁)接受了核磁共振成像脑部扫描,包括静息状态序列和完成共情自我报告测量。种子到全脑静息状态的功能连通性分析表明,更高的情感共情(情感分享和共情痛苦)与默认模式网络(DMN)关键枢纽与大脑其他广泛区域之间的连通性较弱有关。对静息状态网络的分析表明,较高的认知共情与DMN背侧区域与DMN外区域(包括中央前回、后回和小脑)之间的连接强弱相关。更高的情感共享与更大的前显性网络与中央前回和后回之间的连通性有关。然而,这些关联经不起多个模型的修正。虽然解释应该谨慎,但研究结果表明,广泛和分散的连接模式可能与儿童共情的几个组成部分有关。这些发现可能表明,儿童时期共情过程的神经关联更为复杂,专业化程度较低,区域和网络的参与范围更广。未来的研究应该尝试使用不同的测量方法来重复这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Empathy and resting-state functional connectivity in children

Empathy, which is important for social functioning and mental health, is recognized to have both cognitive and affective components. While several studies have demonstrated unique neural underpinnings of empathy components in adults, few have investigated this in young people. Investigating associations between empathy and brain functional connectivity during childhood is beneficial to begin to build a comprehensive picture of the neural correlates of empathy across the lifespan. One hundred and twelve children (52% female, mean age 10 years) underwent magnetic resonance imaging brain scans including a resting-state sequence and completed empathy self-report measures. Seed-to-whole-brain resting-state functional connectivity analyses demonstrated that higher affective empathy (affective sharing and empathic distress) was associated with weaker connectivity between key hubs of the default mode network (DMN) and other widespread areas in the brain. Analyses of resting-state networks demonstrated that higher cognitive empathy was associated with both stronger and weaker connectivity between dorsal and lateral regions of the DMN and regions outside of the DMN, including the pre- and postcentral gyrus, and the cerebellum. Higher affective sharing was associated with greater connectivity between the anterior salience network and the pre- and postcentral gyrus. However, these associations did not withstand correction for multiple models. While interpretations should be made cautiously, findings suggest wide-ranging and diffuse connectivity patterns may be related to several components of empathy in children. These findings could indicate a more complex picture of the neural correlates of empathy processes in childhood, with less specialization and more widespread involvement of regions and networks. Future studies should attempt to replicate these findings using different measurement approaches.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Neuroimage. Reports
Neuroimage. Reports Neuroscience (General)
CiteScore
1.90
自引率
0.00%
发文量
0
审稿时长
87 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信