乌干达穆本德地区转诊医院使用米索前列醇的母婴因素

O. Kizito, Denis Komaketch
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引用次数: 0

摘要

米索前列醇在产科有许多用途。它通过使子宫强烈收缩以及软化和扩张宫颈来模仿正常分娩过程。这个动作使它成为子宫补品。产妇的用途包括宫颈成熟、分娩、治疗不完全流产、预防和治疗产后出血以及堕胎。本研究旨在确定在穆本德地区转诊医院分娩的母亲中与米索前列醇使用相关的母婴风险因素。采用混合方法对母亲、婴儿和医疗保健专业人员进行横断面分析设计。385名受访者参与了调查。访谈、观察和文件审查被用于收集数据。12.4%的母亲曾经使用过米索前列醇。与生活在农村地区的母亲相比,城市母亲有米索前列醇使用阳性史的可能性是其他母亲的两倍(COR=1.843,95%CI(0.903-3.763))。产次为2-4的母亲使用米索前列的可能性低0.5倍[COR=0.514,95%CI(0.166-1.595)]。新生儿的APGAR评分较好,分别为4-7(4次)和8-10(2次),与米索前前列醇使用阳性历史的可能性较高有关。总之,米索前列醇的使用对母亲和胎儿都构成了危险,必须仔细遵守。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
MATERNAL AND FETAL FACTORS ASSOCIATED WITH MISOPROSTOL USE IN MUBENDE REGIONAL REFERRAL HOSPITAL, UGANDA
There are numerous obstetric uses for misoprostol. It mimics the normal labour process by causing the uterus to contract strongly and by softening and dilating the cervix. This action makes it a uterotonic. The maternal uses include cervical ripening, initiating labour, treating incomplete abortions, preventing and treating postpartum haemorrhage, and causing abortions. This study sought to identify maternal and foetal risk factors related to misoprostol use among mothers who gave birth at the regional referral hospital in Mubende. A mixed method analytical cross-sectional design was used with mothers, their infants, and healthcare professionals. 385 respondents made up the sample. Interviews, observation, and the review of documents were used to gather the data. 12.4% of mothers had ever used misoprostol. In comparison to mothers who lived in rural areas, urban mothers were two times more likely to have a positive history of misoprostol usage (COR=1.843, 95% CI (0.903-3.763)). Mothers with a parity of 2–4 had a 0.5x lower likelihood of using misoprostol [COR=0.514, 95% CI (0.166–1.595)]. Better APGAR scores of 4-7 (4 times) and 8-10 (2 times) in newborns were associated with a higher likelihood of a positive history of misoprostol use. In conclusion, misoprostol use poses dangers to both the mother and the foetus, necessitating careful observance.
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