使用移动应用程序进行简短的日常训练对减少强迫症(OCD)症状的有效性:检查“强迫症”的真实世界数据。app -焦虑，情绪和睡眠”

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-01-01 DOI:10.1016/j.jocrd.2023.100782

Avi Gamoran , Guy Doron

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引用次数: 2

摘要

背景:随机对照试验(RCTs)表明，针对强迫症认知的移动交付训练在减轻强迫症症状方面是有效的。然而，在随机对照试验中显示有效的干预措施在现实环境中可能效果较差。方法“强迫症”的真实世界数据。app -焦虑，情绪&“睡眠”用户的收集时间为2020年10月至2022年6月。在基线时评估使用者的强迫症症状、特质和状态情绪得分(T0;n = 46,955)，支付障碍(T1;n = 13,568)，在最终水平(T-final;n = 1732)。结果女性的辍学率较高，且与年龄有关。从T0到T1, OCI-R评分的效应量下降中等(Cohen's d = 0.37)，从T0到T-final, OCI-R评分的效应量下降中等(Cohen's d = 0.66)。在控制人口统计数据和情绪的情况下，效果仍然存在，对于有严重强迫症症状的用户来说，效果最强。16%的重度OCD患者有临床显著改善(OCI-R变化≥21)。虽然稳定的用户特征是短期使用后变化的主要调节因素，但应用使用指标在较长训练期间更为显著。结论真实世界的数据支持强迫症的有效性。可以减轻强迫症症状的应用程序

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Effectiveness of brief daily training using a mobile app in reducing obsessive compulsive disorder (OCD) symptoms: Examining real world data of “OCD.app - Anxiety, mood & sleep”

Background

Randomized controlled trials (RCTs) indicate that mobile delivered training targeting OCD cognitions is effective in reducing OCD symptoms. However, interventions shown to be effective in RCTs may be less effective in real world settings.

Methods

Real world data of “OCD.app - Anxiety, Mood & Sleep” users was collected from October 2020 to June 2022. Users’ OCD symptoms, trait and state mood scores were evaluated at baseline (T0; n = 46,955), payment barrier (T1; n = 13,568), and at the final level (T-final; n = 1732).

Results

Dropout rates were higher for women and associated with younger age. Medium effect size reductions in OCI-R scores from T0 to T1 (Cohen's d = 0.37) and medium-large (Cohen's d = 0.66) reductions from T0 to T-final were found. Effects remained when controlling for demographic data and mood and were strongest for users with severe OCD symptoms. Clinically significant improvement (OCI-R change ≥21) was found in 16% of users with severe OCD symptoms. Although stable user traits were prominent moderators of change following short-term use, app usage indicators were more notable over longer training periods.

Conclusions

Real world data supports the effectiveness of OCD.app for reducing the full range of OCD symptoms.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.