绵羊双杀性Orf病变合并感染细菌的耐药性谱

E. Pastor, Crinu Mesteșanu, P. Pojar, M. Spînu
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引用次数: 0

摘要

兽医中的抗生素耐药性最近在治疗成功方面带来了越来越大的风险,并威胁到各种细菌感染患者的生命。环境细菌很可能在绵羊orf病毒诱导的初始病变上发展,恶化疾病的发展和预后。这项研究旨在验证这样一种假设,即细菌的持久性以及orf病变严重程度的增加是由于共同感染细菌的高抗生素耐药性造成的。使用的抗生素有庆大霉素、头孢呋辛、阿莫西林-克拉维酸、恩诺沙星、环丙沙星、青霉素和三羟美他林。计算每个菌株的多种抗生素耐药性指数。根据MAR指数,至少有两种被调查的环境细菌菌株可能会使orf病变进一步复杂化,并延迟抗生素治疗的积极效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibiotic Resistance Profile in Co-Infecting Bacteria Isolated from Sheep Dipslaying Orf Lesions
Antibiotic resistance in veterinary medicine poses lately increasing risks in therapeutic success and threatens the life of patients with various bacterial infections. Environmental bacteria are very likely to develop on the initial lesions induced by orf virus in sheep, worsening the development and prognosis of the disease. The research aimed at verifying the hypothesis that the persistence of the bacteria and thus, increased severity of the orf lesions is residing in the high antibiotic resistance of the co-infecting bacteria. The antibiotics used were gentamicine, cefuroxime, amoxicilline clavulanic acid, enrofloxacin, ciprofloxacin, penicillin and thrimetoprim. Multi antibiotic resistance indices were calculated for each strain. Based on the MAR index, at least two of the investigated environmental bacteria strains could further complicate orf lesions and delay the positive effects of the antibiotic therapy.
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