阿尔茨海默病及其可能的治疗方法综述

A. Chakraborty, Anil Diwan
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引用次数: 1

摘要

阿尔茨海默病(AD)的特征是记忆力逐渐丧失,再也无法恢复正常,这被称为痴呆症,是由功能性神经细胞死亡引起的。只有10-15%的病例被发现与基因有关。然而,在所有AD病例中,β -淀粉样蛋白(Aβ)形成斑块,tau蛋白形成缠结,破坏正常的神经功能,如运输神经递质、营养物质以及与其他神经细胞的通信;最终患上这种疾病。我们在这里回顾了目前可用的所有治疗方案,并讨论了为什么以及如何开发更好的AD治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Alzheimer and It’s Possible Therapy: A Review
Alzheimer disease (AD) is recognized by a gradual loss of memory which never returns to normal, called dementia caused due to the death of functional neural cells. Only 10-15% cases are found genetically involved. However, in all the cases of AD, beta amyloid (Aβ) protein forms plaques, and the tau protein forms tangles which disrupts the normal neuronal functions for transporting neurotransmitters, nutrient, and also communication with other neural cells; ultimately develops the disease. We have reviewed here the presently available all the treatment options, and discussed, not only why but how, a better option can be developed for AD treatment.
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