{"title":"阿尔茨海默病及其可能的治疗方法综述","authors":"A. Chakraborty, Anil Diwan","doi":"10.33696/NEUROL.1.019","DOIUrl":null,"url":null,"abstract":"Alzheimer disease (AD) is recognized by a gradual loss of memory which never returns to normal, called dementia caused due to the death of functional neural cells. Only 10-15% cases are found genetically involved. However, in all the cases of AD, beta amyloid (Aβ) protein forms plaques, and the tau protein forms tangles which disrupts the normal neuronal functions for transporting neurotransmitters, nutrient, and also communication with other neural cells; ultimately develops the disease. We have reviewed here the presently available all the treatment options, and discussed, not only why but how, a better option can be developed for AD treatment.","PeriodicalId":73744,"journal":{"name":"Journal of experimental neurology","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Alzheimer and It’s Possible Therapy: A Review\",\"authors\":\"A. Chakraborty, Anil Diwan\",\"doi\":\"10.33696/NEUROL.1.019\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Alzheimer disease (AD) is recognized by a gradual loss of memory which never returns to normal, called dementia caused due to the death of functional neural cells. Only 10-15% cases are found genetically involved. However, in all the cases of AD, beta amyloid (Aβ) protein forms plaques, and the tau protein forms tangles which disrupts the normal neuronal functions for transporting neurotransmitters, nutrient, and also communication with other neural cells; ultimately develops the disease. We have reviewed here the presently available all the treatment options, and discussed, not only why but how, a better option can be developed for AD treatment.\",\"PeriodicalId\":73744,\"journal\":{\"name\":\"Journal of experimental neurology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of experimental neurology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33696/NEUROL.1.019\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of experimental neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33696/NEUROL.1.019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Alzheimer disease (AD) is recognized by a gradual loss of memory which never returns to normal, called dementia caused due to the death of functional neural cells. Only 10-15% cases are found genetically involved. However, in all the cases of AD, beta amyloid (Aβ) protein forms plaques, and the tau protein forms tangles which disrupts the normal neuronal functions for transporting neurotransmitters, nutrient, and also communication with other neural cells; ultimately develops the disease. We have reviewed here the presently available all the treatment options, and discussed, not only why but how, a better option can be developed for AD treatment.