牙科手术后对聚乙二醇/聚乙二醇过敏

IF 0.6 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Science International Pub Date : 2021-11-30 DOI:10.1002/osi2.1126

V. Harper, Safiyah Nasser, S. Nasser

{"title":"牙科手术后对聚乙二醇/聚乙二醇过敏","authors":"V. Harper, Safiyah Nasser, S. Nasser","doi":"10.1002/osi2.1126","DOIUrl":null,"url":null,"abstract":"Background: Polyethylene glycols (PEGs) are polyether compounds widely used as excipients within the pharmaceutical industry. PEG allergy is rare but increasingly reported as an unexpected cause for anaphylaxis including to the mRNA COVID-19 vaccines. Presentation is usually with anaphylaxis to multiple unrelated drugs/products. Case Presentation: We report a case of a 25-year-old man who had allergic reactions following root canal treatment with Odontopaste and a second reaction after a single dose of phenoxymethylpenicillin (PEG 6000). Allergy investigations confirmed PEG allergy. Conclusion: All dental healthcare practitioners should be aware of a potentially life-threatening allergy to PEG, an excipient often overlooked during investigation of anaphylaxis.","PeriodicalId":44181,"journal":{"name":"Oral Science International","volume":" ","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Allergy to polyethylene glycol/macrogol following dental surgery\",\"authors\":\"V. Harper, Safiyah Nasser, S. Nasser\",\"doi\":\"10.1002/osi2.1126\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Polyethylene glycols (PEGs) are polyether compounds widely used as excipients within the pharmaceutical industry. PEG allergy is rare but increasingly reported as an unexpected cause for anaphylaxis including to the mRNA COVID-19 vaccines. Presentation is usually with anaphylaxis to multiple unrelated drugs/products. Case Presentation: We report a case of a 25-year-old man who had allergic reactions following root canal treatment with Odontopaste and a second reaction after a single dose of phenoxymethylpenicillin (PEG 6000). Allergy investigations confirmed PEG allergy. Conclusion: All dental healthcare practitioners should be aware of a potentially life-threatening allergy to PEG, an excipient often overlooked during investigation of anaphylaxis.\",\"PeriodicalId\":44181,\"journal\":{\"name\":\"Oral Science International\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2021-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oral Science International\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/osi2.1126\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Science International","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/osi2.1126","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

摘要

背景：聚乙二醇（PEG）是一种聚醚类化合物，在制药工业中广泛用作赋形剂。PEG过敏是罕见的，但越来越多的报道称其为包括mRNA新冠肺炎疫苗在内的过敏反应的意外原因。通常表现为对多种不相关的药物/产品过敏。病例介绍：我们报告了一例25岁的男性患者，他在根管治疗Odontopaste后出现过敏反应，并在单剂量苯氧甲基青霉素（PEG 6000）后出现第二次反应。过敏调查证实PEG过敏。结论：所有牙科保健从业者都应该意识到对PEG的潜在威胁生命的过敏，PEG是一种在过敏反应调查中经常被忽视的赋形剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Allergy to polyethylene glycol/macrogol following dental surgery

Background: Polyethylene glycols (PEGs) are polyether compounds widely used as excipients within the pharmaceutical industry. PEG allergy is rare but increasingly reported as an unexpected cause for anaphylaxis including to the mRNA COVID-19 vaccines. Presentation is usually with anaphylaxis to multiple unrelated drugs/products. Case Presentation: We report a case of a 25-year-old man who had allergic reactions following root canal treatment with Odontopaste and a second reaction after a single dose of phenoxymethylpenicillin (PEG 6000). Allergy investigations confirmed PEG allergy. Conclusion: All dental healthcare practitioners should be aware of a potentially life-threatening allergy to PEG, an excipient often overlooked during investigation of anaphylaxis.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Oral Science International DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

1.00

自引率

20.00%

发文量