精索静脉曲张患者精子和外周血气的比较及其与精子图模式和精索静脉曲张分级的相关性。

IF 2.1 4区 医学 Q2 OBSTETRICS & GYNECOLOGY
Human Fertility Pub Date : 2023-12-01 Epub Date: 2022-03-10 DOI:10.1080/14647273.2022.2046294
Hossein Dialameh, Farshad Namdari, Mohammad Javad Nazarpour, Mahdi Gouravani, Mehrdad Mahalleh, Masoud Bahoush, Alireza Marjooee, Mahdi Ramezani-Binabaj, Mohammad Reza Nikoobakht, Mahsa Kiani
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引用次数: 0

摘要

不孕和精索静脉曲张之间的关系仍然是一个有争议的话题。本研究旨在探讨不育患者精索静脉和外周静脉的静脉血气(VBG)模式与精索静脉曲张分级和精子图变量之间的关系。本研究共纳入47例精索静脉曲张患者。同时从精索静脉和外周静脉抽取血样。分析了这些样品的pH值、氧分压、二氧化碳分压、氧饱和度和碳酸氢盐值。参与者的平均年龄为30.48岁 ± 精液的平均体积为3.92 ± 1.57 mL,精液平均pH值为7.88 ± 0.22。pH值较高(p < 0.01)。然而,包括pO2(p = 0.662)、pCO2(p < 0.001)、血清HCO3浓度(p < 0.01)和碱过量(p = 0.172)与外周静脉相比更低。精索静脉曲张患者精索静脉VBGs决定因素和精子形态和运动能力之间的相关性不显著。总之,尽管VBG的临床意义是明显的,但对精索静脉曲张患者VBG的研究有限。我们应该考虑到,血气的偏差可能是理解精索静脉曲张病理生理学的拼图中缺失的一块。通过更准确地了解病理生理学,我们可以更好地为患者决定理想的治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of spermatic and peripheral blood gases and their correlation with spermogram pattern and varicocele grade in patients with a varicocele.

The relationship between infertility and varicocele is still a controversial topic. This study aimed to find the association between the venous blood gas (VBG) pattern of the spermatic veins and peripheral veins with varicocele grade and spermogram variables in infertile patients. A total of 47 patients with a varicocele were enrolled in this study. Blood samples were drawn simultaneously from the spermatic vein and a peripheral vein. The pH, partial pressure of oxygen, the partial pressure of carbon dioxide, oxygen saturation, and bicarbonate values of these samples were analysed. The mean age of participants was 30.48 ± 6.08. The mean volume of semen was 3.92 ± 1.57 mL, and the mean semen pH was 7.88 ± 0.22. The pH was higher (p < 0.01) in the spermatic vein compared with the peripheral vein. However, level of other parameters including pO2 (p = 0.662), pCO2 (p < 0.001), HCO3 concentration of serum (p < 0.01), and base excess (p = 0.172) were lower in the spermatic vein in comparison with the peripheral vein. Correlations between VBGs determinants of the varicocele patients' spermatic vein and sperm morphology and motility were insignificant. In conclusion, although the clinical significance of VBGs is evident, there are limited studies that investigated the VBGs in varicocele patients. We should consider that the deviation in blood gases may be the missing piece in the puzzle to understand the pathophysiology of varicocele. By knowing the pathophysiology more precisely, we can better decide the ideal treatment option for the patients.

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来源期刊
Human Fertility
Human Fertility OBSTETRICS & GYNECOLOGY-REPRODUCTIVE BIOLOGY
CiteScore
3.30
自引率
5.30%
发文量
50
期刊介绍: Human Fertility is a leading international, multidisciplinary journal dedicated to furthering research and promoting good practice in the areas of human fertility and infertility. Topics included span the range from molecular medicine to healthcare delivery, and contributions are welcomed from professionals and academics from the spectrum of disciplines concerned with human fertility. It is published on behalf of the British Fertility Society. The journal also provides a forum for the publication of peer-reviewed articles arising out of the activities of the Association of Biomedical Andrologists, the Association of Clinical Embryologists, the Association of Irish Clinical Embryologists, the British Andrology Society, the British Infertility Counselling Association, the Irish Fertility Society and the Royal College of Nursing Fertility Nurses Group. All submissions are welcome. Articles considered include original papers, reviews, policy statements, commentaries, debates, correspondence, and reports of sessions at meetings. The journal also publishes refereed abstracts from the meetings of the constituent organizations.
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