标记辅助筛选奶牛β-酪蛋白A2基因变异株

IF 3.3 4区农林科学 Q2 FOOD SCIENCE & TECHNOLOGY

Italian Journal of Food Science Pub Date : 2022-04-02 DOI:10.15586/ijfs.v34i2.2178

C. Sebastiani, Chiara Arcangeli, Martina Torricelli, M. Ciullo, N. D’avino, Giulia Cinti, S. Fisichella, M. Biagetti

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引用次数: 10

摘要

许多研究强调了β-酪蛋白A1与特定人类疾病和牛奶的轻微消化率之间的潜在联系，因为在消化过程中释放了生物活性肽β-酪蛋白7（BCM-7）。相反，祖先的β-酪蛋白A2变体似乎是一个有利的特性，因为它与BMC-7的释放无关。这项工作的目的是评估用A2纯合子精液受精的先前基因型奶牛后代中β-酪蛋白变体的频率。A2/A2动物的频率几乎翻了一番，从37%增加到69%。从实现生产A2牛奶的目标来看，这些都是令人鼓舞的结果。

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Marker-assisted selection of dairy cows for β-casein gene A2 variant

Many studies highlighted potential associations of β-casein A1 with specific human diseases and a minor digestibility of milk, due to the bioactive peptide β-casomorphin 7 (BCM-7) release during digestion. Conversely, the ancestral β-casein A2 variant seems to be a favorable trait because it is not associated with BMC-7 release. The aim of this work was to evaluate frequencies of β-casein variants in offspring of previously genotyped cows inseminated with A2 homozygous semen. The frequency of the A2/A2 animals has almost doubled from 37 to 69%. These are encouraging results with the perspective of reaching the goal of producing A2 milk.

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来源期刊

Italian Journal of Food Science 工程技术-食品科技

CiteScore

4.20

自引率

0.00%

发文量

审稿时长

>36 weeks

期刊介绍： "Italian Journal of Food Science" is an international journal publishing original, basic and applied papers, reviews, short communications, surveys and opinions on food science and technology with specific reference to the Mediterranean Region. Its expanded scope includes food production, food engineering, food management, food quality, shelf-life, consumer acceptance of foodstuffs, food safety and nutrition, energy and environmental aspects of food processing on the whole life cycle. Reviews and surveys on specific topics relevant to the advance of the Mediterranean food industry are particularly welcome.