治疗性生物制剂的眼部不良反应

IF 2.3 Q2 OPHTHALMOLOGY

Therapeutic Advances in Ophthalmology Pub Date : 2022-01-01 DOI:10.1177/25158414211070878

H. V. Neves da Silva, J. Placide, Anne A Duong, Y. Ronquillo, S. McCabe, M. Moshirfar

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引用次数: 0

摘要

生物药物，称为生物制剂，是含有或来源于活生物体(人、动物或微生物)的药物。随着新的生物制剂每年被美国食品和药物管理局(FDA)批准，临床医生需要了解与这些药物相关的潜在眼部不良反应。本文综述了用于治疗眼科和非眼科疾病的生物药物对眼部的不良反应。我们在PubMed检索了有关生物制剂引起眼部不良反应的相关病例报告、病例系列、综述和临床试验。该审查于2021年6月进行，调查了最新(2021年4月)FDA许可生物制品紫书数据库中列出的药物。本文综述了单克隆抗体、白细胞介素和受体融合蛋白的研究进展。我们探讨了33种生物药物的眼部副作用，说明它们是常见的、常见的还是罕见的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Ocular adverse effects of therapeutic biologics

Biological drugs, termed biologics, are medications that contain or are derived from a living organism (human, animal, or microorganism). With new biological agents being approved by the Food and Drug Administration (FDA) every year, clinicians need to know potential ocular adverse effects that are associated with these drugs. This review provides an overview of ocular adverse effects of biological medications used to treat both ophthalmic and non-ophthalmic diseases. We searched PubMed for relevant case reports, case series, reviews, and clinical trials reporting ocular adverse effects caused by biologics. This review was conducted in June 2021 and investigated the drugs listed in the most updated (April 2021) FDA Purple Book Database of Licensed Biological Products. This review focuses on monoclonal antibodies, interleukins, and receptor fusion proteins. We explore ocular side effects of 33 biological drugs, stating whether they are frequent, common, or rare.

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来源期刊

Therapeutic Advances in Ophthalmology OPHTHALMOLOGY-

CiteScore

4.50

自引率

0.00%

发文量

审稿时长

12 weeks