西里西亚省(波兰)前列腺癌根治术前后癌症患者健康相关生活质量的纵向观察试验研究

Tomasz Jurys, B. Burzyński, Andrzej Kupilas
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引用次数: 0

摘要

介绍近年来,患者报告的结果在评估治疗效果方面发挥着越来越重要的作用,作为与健康相关的生活质量(如身体、情感和心理社会)的一个方面,并在选择治疗方法和补充管理(如护理或理疗)时予以考虑。客观的这项试点研究的目的是评估癌症患者在前列腺癌根治术前和术后3个月与健康相关的生活质量的变化。这项研究的主要动机是少数研究使用经验证的工具来评估患有癌症的波兰人群中男性的生活质量。材料和方法。这项研究涉及31名新确诊的癌症前列腺癌患者,他们有资格接受前列腺癌根治术。使用EORTC QLQ-C30和EORTC QLQ-PR25问卷进行两次生活质量评估,第一次在手术前,第二次在手术后3个月。后果基线和3个月随访结果的比较显示,患者在各个领域的生活质量显著恶化,在情感、社会和角色功能量表上观察到临床和统计上最显著的变化。结论。根治性前列腺切除术导致术后3个月生活质量下降。生活质量的心理社会领域比生理领域受到的影响更大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Health-related quality of life in prostate cancer patients in the Silesian Province (Poland) before and after radical prostatectomy – a longitudinal observational pilot study
Introduction. In recent years, patient-reported outcomes have played an increasingly important role in the evaluation of the effectiveness of treatments as aspects of health-related quality of life (e.g. physical, emotional, and psychosocial), and are taken into account in the selection of treatment methods and complementary management (e.g. nursing care or physiotherapy). Objective . The aim of this pilot study was to assess changes in the health-related quality of life in a prostate cancer population before and 3 months after radical prostatectomy. The main motivation for the study is the small number of studies using validated tools to assess the quality of life of men in the Polish population suffering from prostate cancer. Materials and method . The study concerned 31 newly-diagnosed prostate cancer patients who qualified for radical prostatectomy. Quality of life assessment was performed twice – first before surgery, and then 3 months afterwards – using the EORTC QLQ-C30 and EORTC QLQ-PR25 questionnaires. Results . Comparison of baseline and 3-month follow-up results revealed significant deteriorations in patients’ quality of life across various domains, with the clinically and statistically most significant changes being observed on the emotional, social, and role functioning scales. Conclusions. Radical prostatectomy contributed to decreased quality of life 3 months postoperatively. The psychosocial domains of the quality of life are more strongly affected than the physical domains.
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