赣州市大气颗粒物污染浓度与高血压住院率的关系

IF 1.9 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE
Chenwei Li, Xinye Zhou, Kun Huang, Xiaokang Zhang, Yanfang Gao
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引用次数: 1

摘要

细颗粒物(PM2.5)和可吸入颗粒物(PM10)是对心血管系统具有毒性作用的两种主要空气污染物。高血压作为一种慢性非传染性心血管疾病,也是多种疾病的危险因素。我们应用具有准泊松链接的广义线性模型来评估空气污染暴露对高血压患者每日入院人数的影响。此外,我们建立了双污染物模型,通过调整其他气态污染物来评价PM2.5和PM10危害效应的稳定性。结果表明,研究期间,24 h环境PM2.5和PM10平均浓度分别为38.17和59.84 μg/m3,共记录了2611例高血压住院病例。空气污染浓度显著影响接触后约2个月高血压住院人数。在单一污染物模型中,PM2.5和PM10每增加10 μg/m3,在影响最强的滞后日,高血压住院人数分别增加7.92% (95% CI: 5.48% ~ 10.42%)和4.46% (95% CI: 2.86% ~ 5.65%)。NO2、O3、CO和SO2对同期住院人数有不同的显著影响,PM2.5和PM10通过双污染物模型调整后仍表现出显著的显著影响。这些发现可能有助于更好地了解环境颗粒物对健康的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association between Particulate Matter Pollution Concentration and Hospital Admissions for Hypertension in Ganzhou, China
Fine particulate matter (PM2.5) and respirable particulate matter (PM10) are two major air pollutants with toxic effects on the cardiovascular system. Hypertension, as a chronic noncommunicable cardiovascular disease, is also a risk factor for several diseases. We applied generalized linear models with a quasi-Poisson link to assess the effect of air pollution exposure on the number of daily admissions for patients with hypertension. In addition, we established a two-pollutant model to evaluate PM2.5 and PM10 hazard effect stability by adjusting the other gaseous pollutants. Results showed that during the study period, 24 h mean concentrations of ambient PM2.5 and PM10 at 38.17 and 59.84 μg/m3, respectively, and a total of 2,611 hypertension hospital admissions were recorded. Air pollution concentrations significantly affected the number of hospitalizations for hypertension approximately 2 months after exposure. For each 10 μg/m3 increase in PM2.5 and PM10 in single-pollutant models, the number of hospitalizations for hypertension increased by 7.92% (95% CI: 5.48% to 10.42%) and 4.46% (95% CI: 2.86% to 5.65%), respectively, at the lag day with the strongest effect. NO2, O3, CO, and SO2 had different significant effects on the number of hospitalizations over the same time period, and PM2.5 and PM10 still showed robust significant effects after adjustment of gas pollutants through a two-pollutant model. These findings may contribute to a better understanding of the health effects of ambient particulate matter.
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来源期刊
International Journal of Hypertension
International Journal of Hypertension Medicine-Internal Medicine
CiteScore
4.00
自引率
5.30%
发文量
45
期刊介绍: International Journal of Hypertension is a peer-reviewed, Open Access journal that provides a forum for clinicians and basic scientists interested in blood pressure regulation and pathophysiology, as well as treatment and prevention of hypertension. The journal publishes original research articles, review articles, and clinical studies on the etiology and risk factors of hypertension, with a special focus on vascular biology, epidemiology, pediatric hypertension, and hypertensive nephropathy.
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