香蜂草中迷迭香酸的提取工艺优化

Q4 Agricultural and Biological Sciences

Nova Biotechnologica et Chimica Pub Date : 2021-11-22 DOI:10.36547/nbc.1275

M. Ondrejovič, H. Benkovičová, S. Šilhár

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引用次数: 3

摘要

本研究的目的是优化从柠檬风油精（Melissa officinalis）中提取迷迭香酸的工艺。采用响应面法（RSM）确定了从柠檬油膏中提取迷迭香酸的最佳工艺条件。采用中心堆肥设计（CCD）研究了固液比、溶剂组成（%）和萃取温度（°C）三个自变量的影响。因变量是迷迭香酸的产量。二阶多项式模型用于预测响应。迷迭香酸的最佳工艺条件为：PEME1:29（w/v），温度66°C，丙-2-醇含量34%。实验值与95%置信区间内的预测值一致。通过这些优化的条件提取迷迭香酸的产率达到72.6mg迷迭香酸/g干提取物质。

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Optimization of rosmarinic acid extraction from lemon balm (Melissa officinalis)

The aim of this study was optimization of rosmarinic acid extraction from lemon balm (Melissa officinalis). The optimal conditions for the extraction of rosmarinic acid from lemon balm were determined using response surface methodology (RSM). A center composide design (CCD) was used to investigate the effects of three independent variables, namely solid-liquid radio, solvent composition (%) and extraction temperature (°C). Dependent variable was yield of rosmarinic acid. A second-order polynomial model was used for predicting the response. Optimized conditions for rosmarinic acid were: PEME 1:29 (w/v), temperature 66 °C a % propan-2-ol 34 %. The experimental values agreed with predicted within a 95 % confidence interval. Yield of rosmarinic acid extraction by these optimized conditions was achieved 72.6 mg of rosmarinic acid / g of dry extraction matter.

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来源期刊

Nova Biotechnologica et Chimica Agricultural and Biological Sciences-Food Science

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

24 weeks