Can Alcohol and Obesity be Considered Risk Factors for Diabetes Mellitus? (environmental study)

Rationale: The literature recognizes a causal relationship between alcohol consumption and the burden of noncommunicable chronic disease (NCD). Objective: To investigate the relationship between the maximum and minimum consumption of alcoholic beverages (AB) and metabolic syndrome (MS), the burden of diabetes mellitus, pancreatic cancer, nephritis and alcoholism in 158 countries in 2004. Methods: U-Mann-Whitney test (UMY) and multiple linear regression analysis (MRA) were used for data analysis; GBD databases 2004; FAO 1990-2005. Results: Studies have shown that the maximum and minimum consumption of alcoholic beverages (AP) in the countries of the world differed 108 times and amounted to 343 grams per person per day, excluding gender and age (p≤0.001). The 20 countries with the highest AB versus the 20 countries with the lowest AB were 14 times higher per capita income (p≤0.001); the burden of pancreatic cancer is 3.5 times higher in men and women (p≤0.001); the burden of alcoholism is 8 times higher for men, 18 times for women (p≤0.001); 2 times in men, the burden of diabetes mellitus is 3 times lower in women and the burden of nephritis is 7 times lower in men and women (p≤0.001). In countries with maximum AB, the predictors of metabolic syndrome - MS (% of men and women in a country with MS impairment) were 2 times higher (p≤0.001). Conclusions: In countries with the highest AB consumption, the burden of alcoholism and pancreatic cancer is several times higher predictors of MS, but the burden of diabetes and nephritis is lower. Gender differences in the studied characteristics are noted. Further research is needed on the nature of the relationship between alcohol consumption and NCD to develop prevention methods.