先天性心脏病合并肺动脉高压患儿右心室形态学的临床价值

中国综合临床 Pub Date : 2019-11-01 DOI:10.3760/CMA.J.ISSN.1008-6315.2019.06.008

Xue-jiao Zhang, Qiaolan Zhou, Qingqiang Qian, Yanmin Kan

{"title":"先天性心脏病合并肺动脉高压患儿右心室形态学的临床价值","authors":"Xue-jiao Zhang, Qiaolan Zhou, Qingqiang Qian, Yanmin Kan","doi":"10.3760/CMA.J.ISSN.1008-6315.2019.06.008","DOIUrl":null,"url":null,"abstract":"Objective \nTo investigate clinical value of right ventricular morphology in children with congenital heart disease associated pulmonary hypertension. \n \n \nMethods \nFrom October 2014 to October 2017, 37 children with congenital heart disease without associated pulmonary hypertension (resting pulmonary systolic pressure ≤ 30 mmHg, 1 mmHg=0.133 kPa) were selected as group A. Thirty-seven children with congenital heart disease and associated pulmonary hypertension (resting pulmonary systolic pressure>30 m). were in group B, and 37 healthy children were in control group.Echocardiography was performed to compare the results of right ventricular morphology and systolic function in three groups. \n \n \nResults \n(1)Right ventricular morphology indexes: right atrium upper and lower diameter((56.8±4.0) mm), right atrium left and right diameter((49.2±3.3) mm), right ventricle basal segment inner diameter((43.7±2.5) mm), right ventricle medial diameter((41.7±3.9) mm), right ventricle long axis distance((73.4±6.2) mm), sternum sidelines right ventricular outflow tract proximal end diameter((37.8±2.4) mm), short axis view right ventricular outflow tract distal internal diameter((33.6±2.1) mm), main pulmonary artery internal diameter((30.5±2.5)mm), right ventricle end diastolic area((31.6±1.8) cm2), right ventricle end systolic area((19.0±2.7) cm2)in group B were higher than those in group A((46.2±3.1) mm, (40.4±2.8) mm, (34.6±2.2) mm, (32.5±2.6) mm, (65.1±4.7) mm, (30.2±2.0) mm, (29.4±1.8) mm, (23.0±1.6) mm, (22.5±1.1) cm2, (11.6±1.2) cm2)and control group((45.3±2.6) mm, (39.5±1.7) mm, (34.0±1.9) mm, (31.8±2.0) mm, (63.2±3.8) mm, (29.6±1.7) mm, (28.9±1.5) mm, (22.4±1.4) mm, (22.1±1.0) cm2, (11.3±0.9) cm2), (F=140.26, 147.47, 223.08, 130.46, 43.56, 183.33, 74.71, 209.94, 587.99, 221.34, all P<0.01 ). (2)Right ventricle contractile function indexes : right ventricular area change rate((40.1±1.6)%), three tricuspid ring systolic displacement((2.2±0.2) cm), tricuspid valve peak systolic flow velocity((13.8±0.9) cm/s)in group B were lower than those in group A((46.3±1.7)%, (2.5±0.3) cm, (16.7±1.2) cm/s)and control group((46.8±1.5)%, (2.6±0.3) cm, (17.2±1.4) cm/s), the difference was statistically significant(F=200.81, 21.86, 88.85, all P<0.01 ). \n \n \nConclusion \nChildren with congenital heart disease associated pulmonary hypertension have right ventricle morphological changes and right ventricular systolic function decreasing.Right ventricular morphological examination has important clinical value. \n \n \nKey words: \nCongenital heart disease associated pulmonary hypertension; Right ventricular morphology; Children","PeriodicalId":10365,"journal":{"name":"中国综合临床","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical value of right ventricular morphology in children with congenital heart disease associated pulmonary hypertension\",\"authors\":\"Xue-jiao Zhang, Qiaolan Zhou, Qingqiang Qian, Yanmin Kan\",\"doi\":\"10.3760/CMA.J.ISSN.1008-6315.2019.06.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective \\nTo investigate clinical value of right ventricular morphology in children with congenital heart disease associated pulmonary hypertension. \\n \\n \\nMethods \\nFrom October 2014 to October 2017, 37 children with congenital heart disease without associated pulmonary hypertension (resting pulmonary systolic pressure ≤ 30 mmHg, 1 mmHg=0.133 kPa) were selected as group A. Thirty-seven children with congenital heart disease and associated pulmonary hypertension (resting pulmonary systolic pressure>30 m). were in group B, and 37 healthy children were in control group.Echocardiography was performed to compare the results of right ventricular morphology and systolic function in three groups. \\n \\n \\nResults \\n(1)Right ventricular morphology indexes: right atrium upper and lower diameter((56.8±4.0) mm), right atrium left and right diameter((49.2±3.3) mm), right ventricle basal segment inner diameter((43.7±2.5) mm), right ventricle medial diameter((41.7±3.9) mm), right ventricle long axis distance((73.4±6.2) mm), sternum sidelines right ventricular outflow tract proximal end diameter((37.8±2.4) mm), short axis view right ventricular outflow tract distal internal diameter((33.6±2.1) mm), main pulmonary artery internal diameter((30.5±2.5)mm), right ventricle end diastolic area((31.6±1.8) cm2), right ventricle end systolic area((19.0±2.7) cm2)in group B were higher than those in group A((46.2±3.1) mm, (40.4±2.8) mm, (34.6±2.2) mm, (32.5±2.6) mm, (65.1±4.7) mm, (30.2±2.0) mm, (29.4±1.8) mm, (23.0±1.6) mm, (22.5±1.1) cm2, (11.6±1.2) cm2)and control group((45.3±2.6) mm, (39.5±1.7) mm, (34.0±1.9) mm, (31.8±2.0) mm, (63.2±3.8) mm, (29.6±1.7) mm, (28.9±1.5) mm, (22.4±1.4) mm, (22.1±1.0) cm2, (11.3±0.9) cm2), (F=140.26, 147.47, 223.08, 130.46, 43.56, 183.33, 74.71, 209.94, 587.99, 221.34, all P<0.01 ). (2)Right ventricle contractile function indexes : right ventricular area change rate((40.1±1.6)%), three tricuspid ring systolic displacement((2.2±0.2) cm), tricuspid valve peak systolic flow velocity((13.8±0.9) cm/s)in group B were lower than those in group A((46.3±1.7)%, (2.5±0.3) cm, (16.7±1.2) cm/s)and control group((46.8±1.5)%, (2.6±0.3) cm, (17.2±1.4) cm/s), the difference was statistically significant(F=200.81, 21.86, 88.85, all P<0.01 ). \\n \\n \\nConclusion \\nChildren with congenital heart disease associated pulmonary hypertension have right ventricle morphological changes and right ventricular systolic function decreasing.Right ventricular morphological examination has important clinical value. \\n \\n \\nKey words: \\nCongenital heart disease associated pulmonary hypertension; Right ventricular morphology; Children\",\"PeriodicalId\":10365,\"journal\":{\"name\":\"中国综合临床\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国综合临床\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1008-6315.2019.06.008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国综合临床","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1008-6315.2019.06.008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

目的探讨先天性心脏病合并肺动脉高压患儿右心室形态学的临床价值。方法2014年10月~ 2017年10月选取37例先天性心脏病合并肺动脉高压患儿(静息肺收缩压≤30 mmHg, 1 mmHg=0.133 kPa)作为a组，37例先天性心脏病合并肺动脉高压患儿(静息肺收缩压bbb30 m)作为B组，37例健康患儿作为对照组。超声心动图比较三组患者右心室形态和收缩功能的变化。结果(1)右心室形态学指标:右心房上下内径((56.8±4.0)mm)、右心房左右内径((49.2±3.3)mm)、右心室基底段内径((43.7±2.5)mm)、右心室内侧内径((41.7±3.9)mm)、右心室长轴距离((73.4±6.2)mm)、胸骨侧线右心室流出道近端内径((37.8±2.4)mm)、短轴观右心室流出道远端内径((33.6±2.1)mm)、肺动脉主干内径((30.5±2.5)mm)、B组右心室舒张末期面积((31.6±1.8)cm2)、右心室收缩末期面积((19.0±2.7)cm2)均高于A组((46.2±3.1)mm、(40.4±2.8)mm、(34.6±2.2)mm、(65.1±4.7)mm、(30.2±2.0)mm、(29.4±1.8)mm、(23.0±1.6)mm、(22.5±1.1)cm2、(11.6±1.2)cm2)和对照组((45.3±2.6)mm、(39.5±1.7)mm、(34.0±1.9)mm、(31.8±2.0)mm、(63.2±3.8)mm、(29.6±1.7)mm、(28.9±1.5)mm、(22.4±1.4)mm、(22.1±1.0)cm2、(11.3±0.9)cm2)， (F=140.26、147.47、223.08、130.46、43.56、183.33、74.71、209.94、587.99、221.34,P均<0.01)。(2)右心室收缩功能指标:B组右心室面积变化率((40.1±1.6)%)、三尖瓣收缩位移((2.2±0.2)cm)、三尖瓣峰值收缩血流速度((13.8±0.9)cm/s)低于A组((46.3±1.7)%、(2.5±0.3)cm、(16.7±1.2)cm/s)和对照组((46.8±1.5)%、(2.6±0.3)cm、(17.2±1.4)cm/s)，差异均有统计学意义(F=200.81、21.86、88.85，均P<0.01)。结论先天性心脏病合并肺动脉高压患儿右心室形态改变，右心室收缩功能下降。右心室形态学检查具有重要的临床价值。关键词:先天性心脏病相关肺动脉高压;右心室形态;孩子们

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Clinical value of right ventricular morphology in children with congenital heart disease associated pulmonary hypertension

Objective To investigate clinical value of right ventricular morphology in children with congenital heart disease associated pulmonary hypertension. Methods From October 2014 to October 2017, 37 children with congenital heart disease without associated pulmonary hypertension (resting pulmonary systolic pressure ≤ 30 mmHg, 1 mmHg=0.133 kPa) were selected as group A. Thirty-seven children with congenital heart disease and associated pulmonary hypertension (resting pulmonary systolic pressure>30 m). were in group B, and 37 healthy children were in control group.Echocardiography was performed to compare the results of right ventricular morphology and systolic function in three groups. Results (1)Right ventricular morphology indexes: right atrium upper and lower diameter((56.8±4.0) mm), right atrium left and right diameter((49.2±3.3) mm), right ventricle basal segment inner diameter((43.7±2.5) mm), right ventricle medial diameter((41.7±3.9) mm), right ventricle long axis distance((73.4±6.2) mm), sternum sidelines right ventricular outflow tract proximal end diameter((37.8±2.4) mm), short axis view right ventricular outflow tract distal internal diameter((33.6±2.1) mm), main pulmonary artery internal diameter((30.5±2.5)mm), right ventricle end diastolic area((31.6±1.8) cm2), right ventricle end systolic area((19.0±2.7) cm2)in group B were higher than those in group A((46.2±3.1) mm, (40.4±2.8) mm, (34.6±2.2) mm, (32.5±2.6) mm, (65.1±4.7) mm, (30.2±2.0) mm, (29.4±1.8) mm, (23.0±1.6) mm, (22.5±1.1) cm2, (11.6±1.2) cm2)and control group((45.3±2.6) mm, (39.5±1.7) mm, (34.0±1.9) mm, (31.8±2.0) mm, (63.2±3.8) mm, (29.6±1.7) mm, (28.9±1.5) mm, (22.4±1.4) mm, (22.1±1.0) cm2, (11.3±0.9) cm2), (F=140.26, 147.47, 223.08, 130.46, 43.56, 183.33, 74.71, 209.94, 587.99, 221.34, all P<0.01 ). (2)Right ventricle contractile function indexes : right ventricular area change rate((40.1±1.6)%), three tricuspid ring systolic displacement((2.2±0.2) cm), tricuspid valve peak systolic flow velocity((13.8±0.9) cm/s)in group B were lower than those in group A((46.3±1.7)%, (2.5±0.3) cm, (16.7±1.2) cm/s)and control group((46.8±1.5)%, (2.6±0.3) cm, (17.2±1.4) cm/s), the difference was statistically significant(F=200.81, 21.86, 88.85, all P<0.01 ). Conclusion Children with congenital heart disease associated pulmonary hypertension have right ventricle morphological changes and right ventricular systolic function decreasing.Right ventricular morphological examination has important clinical value. Key words: Congenital heart disease associated pulmonary hypertension; Right ventricular morphology; Children

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

中国综合临床

CiteScore

0.10

自引率

0.00%

发文量

16855

期刊介绍： Clinical Medicine of China is an academic journal organized by the Chinese Medical Association (CMA), which mainly publishes original research papers, reviews and commentaries in the field. Clinical Medicine of China is a source journal of Peking University (2000 and 2004 editions), a core journal of Chinese science and technology, an academic journal of RCCSE China Core (Extended Edition), and has been published in Chemical Abstracts of the United States (CA), Abstracts Journal of Russia (AJ), Chinese Core Journals (Selection) Database, Chinese Science and Technology Materials Directory, Wanfang Database, China Academic Journal Database, JST Japan Science and Technology Agency Database (Japanese) (2018) and other databases.