Daniel S Barron, Stephen Heisig, Carla Agurto, Raquel Norel, Brittany Quagan, Albert Powers, Michael L Birnbaum, Todd Constable, Guillermo Cecchi, John H Krystal
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Feasibility Analysis of Phenotype Quantification from Unstructured Clinical Interactions.
We conducted a feasibility analysis to determine the quality of data that could be collected ambiently during routine clinical conversations. We used inexpensive, consumer-grade hardware to record unstructured dialogue and open-source software tools to quantify and model face, voice (acoustic and language) and movement features. We used an external validation set to perform proof-of-concept predictive analyses and show that clinically relevant measures can be produced without a restrictive protocol.