N.T. Dzhaparalieva, A. T. Zhusupova, B.B. Kadyrova, B. B. Kulov
{"title":"罕见家族性脱髓鞘病1例报告","authors":"N.T. Dzhaparalieva, A. T. Zhusupova, B.B. Kadyrova, B. B. Kulov","doi":"10.26577/iam.2023.v4.i1.07","DOIUrl":null,"url":null,"abstract":"Neuromyelitis optica or Devic`s disease is an inflammatory disimmune-neurodegenerative disease characterized by a progressive course, predominantly affecting the optic nerves and spinal cord, with relatively intact brain structures. The differential diagnosis of neuromyelitis optica and multiple sclerosis is based on the identification of a typical clinical and tomographic picture and the presence of a high level of antibodies to aquaporin 4 in the blood serum. We presented a familial clinical case of Devic`s disease in a representative of the indigenous population of Central Asia and the associated difficulties in differential diagnosis. M., 49 years old, was admitted to the Department of Neurology No. 1 of the National Hospital under the Ministry of Health of the Kyrgyz Republic with complaints on decreased vision and a feeling of a “veil” in front of the left eye, blindness on the right, weakness in all limbs, numbness in them, fatigue when walking, dizziness and instability when walking, a feeling of “passing an electric current”.Thus, the onset of the disease in a 49-year-old patient was provoked by a hormonal imbalance – after a medical abortion due to a miscarriage, as well as after a viral infection (herpetic), symptoms of brainstem","PeriodicalId":34543,"journal":{"name":"Interdisciplinary Approaches to Medicine","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A CASE REPORT OF RARE FAMILIAL DEMYELINATING DISEASE\",\"authors\":\"N.T. Dzhaparalieva, A. T. Zhusupova, B.B. Kadyrova, B. B. Kulov\",\"doi\":\"10.26577/iam.2023.v4.i1.07\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Neuromyelitis optica or Devic`s disease is an inflammatory disimmune-neurodegenerative disease characterized by a progressive course, predominantly affecting the optic nerves and spinal cord, with relatively intact brain structures. The differential diagnosis of neuromyelitis optica and multiple sclerosis is based on the identification of a typical clinical and tomographic picture and the presence of a high level of antibodies to aquaporin 4 in the blood serum. We presented a familial clinical case of Devic`s disease in a representative of the indigenous population of Central Asia and the associated difficulties in differential diagnosis. M., 49 years old, was admitted to the Department of Neurology No. 1 of the National Hospital under the Ministry of Health of the Kyrgyz Republic with complaints on decreased vision and a feeling of a “veil” in front of the left eye, blindness on the right, weakness in all limbs, numbness in them, fatigue when walking, dizziness and instability when walking, a feeling of “passing an electric current”.Thus, the onset of the disease in a 49-year-old patient was provoked by a hormonal imbalance – after a medical abortion due to a miscarriage, as well as after a viral infection (herpetic), symptoms of brainstem\",\"PeriodicalId\":34543,\"journal\":{\"name\":\"Interdisciplinary Approaches to Medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Interdisciplinary Approaches to Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26577/iam.2023.v4.i1.07\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Interdisciplinary Approaches to Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26577/iam.2023.v4.i1.07","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A CASE REPORT OF RARE FAMILIAL DEMYELINATING DISEASE
Neuromyelitis optica or Devic`s disease is an inflammatory disimmune-neurodegenerative disease characterized by a progressive course, predominantly affecting the optic nerves and spinal cord, with relatively intact brain structures. The differential diagnosis of neuromyelitis optica and multiple sclerosis is based on the identification of a typical clinical and tomographic picture and the presence of a high level of antibodies to aquaporin 4 in the blood serum. We presented a familial clinical case of Devic`s disease in a representative of the indigenous population of Central Asia and the associated difficulties in differential diagnosis. M., 49 years old, was admitted to the Department of Neurology No. 1 of the National Hospital under the Ministry of Health of the Kyrgyz Republic with complaints on decreased vision and a feeling of a “veil” in front of the left eye, blindness on the right, weakness in all limbs, numbness in them, fatigue when walking, dizziness and instability when walking, a feeling of “passing an electric current”.Thus, the onset of the disease in a 49-year-old patient was provoked by a hormonal imbalance – after a medical abortion due to a miscarriage, as well as after a viral infection (herpetic), symptoms of brainstem