房水细胞学证实非小细胞肺癌虹膜转移

IF 0.1 Q4 OPHTHALMOLOGY
Jiyeon Han, Y. Jang, J. Han
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引用次数: 0

摘要

目的:报告一例经重复房水细胞学检查证实的与非小细胞肺癌相关的虹膜转移。病例总结:一名53岁的女性,在1个月内因视力受损和左眼疼痛而到我们的眼科门诊就诊。在眼科检查中,矫正视力最好的是20/20右眼(OD)和20/32左眼(OS)。使用标准Goldmann压平眼压计测量的眼压为12 mmHg OD和42 mmHg OS。裂隙灯检查显示左眼有多个虹膜结节。13个月前,患者被诊断为NLC,正在接受化疗。尽管进行了最大限度的药物治疗,但眼压没有得到控制。由于怀疑有虹膜转移,行前房穿刺房水取样。细胞学分析没有发现恶性细胞。一周后,重复房水取样。恶性细胞经组织病理学证实。考虑到眼部转移,肿瘤学家改变了化疗方案。结论:当NLC患者出现虹膜结节时,重复房水细胞学检查可以确认虹膜转移。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Iris Metastasis of Non-small-cell Lung Cancer Confirmed via Aqueous Humor Cytology
Purpose: To report an iris metastasis associated with non-small-cell lung cancer (NLC) confirmed via repeat aqueous humor cytology.Case summary: A 53-year-old female presented to our ophthalmology outpatient department with complaints of vision impairment and pain in the left eye 1 month in duration. In ophthalmologic examinations, the best-corrected visual acuities were 20/20 oculus dexter (OD) and 20/32 oculus sinister (OS). The intraocular pressures measured using standard Goldmann applanation tonometery were 12 mmHg OD and 42 mmHg OS. Slit-lamp examination revealed multiple iris nodules in the left eye. Thirteen months prior, the patient had been diagnosed with NLC and was on chemotherapy. Despite the maximal tolerated medical therapy, the intraocular pressure was not controlled. As an iris metastasis was suspected, anterior chamber paracentesis was performed for aqueous humor sampling. Cytological analysis did not reveal malignant cells. One week later, aqueous humor sampling was repeated. Malignant cells were histopathologically confirmed. Given the ocular metastasis, the oncologists changed the chemotherapy regimen.Conclusions: When an NLC patient exhibits iris nodules, repeat aqueous humor cytology can confirm an iris metastasis.
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CiteScore
0.20
自引率
0.00%
发文量
126
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