Miho Hoshi, Saeko Ishida, T. Mashimo
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引用次数: 0
摘要
适当的繁殖…和…存储环境……实验室动物…是必不可少的…为动物…测试…我们…设施……支持……BSL1-3级研究………………主题……是……广泛,…等…………/病毒基因…/细胞疗法……疫苗发展…在………最近……增加……在…移植…实验中,……数字……的……免疫缺陷动物…………也增加了……在……,……实验……用……病毒向量向上趋势…………上下文……这些情况下,……这……一直………………改善需要……动物育种和环境研究……在……这……每个研究……可以……共存…然而,在同一设备…………………其他…,…老化…设施,…缺乏……繁殖…,…和…效率…………设施维护…………已经……问题…………很多……年…………顺序解决……这些…问题,…我们…设施……一直…工作…………简介…………单独的通风系统…………可以…使…成为…一个障碍…2019…每个笼子里……。在…BSL2……繁殖…房间,…,…移植实验…和…病毒主要矢量管理…………执行,……系统…………已经……可能………明显增加…………住宿…我们也……介绍…………检疫…房间里……这……以前……用…………气球……隔离器……这………使…我们……介绍…动物…更多……对…新……任命人员的效率。在…建立的新……老鼠繁殖…,…两个……类型……个人通风…系统……介绍了……根据…………生产的目的………和…维护…在…,…bioBUBBLE…系统,……是……一个……预制……干净的…房间,…是…介绍了……为……目的……的维护……繁殖…的……严重……免疫缺陷…老鼠。在……这……研讨会,…我们……像……介绍……特性、……操作方法问题,…和…未来……问题……几个新…………育种设备介绍。IMSUT动物设施育种设备现状及问题
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LAS Seminar 1
Proper...breeding...and...storage...environment...of... laboratory...animals... is...essential... for...animal... testing....Our... facility... supports...BSL1-3...level...research....The...research...subjects...are...wide-ranging,...such...as...gene.../viral.../...cell...therapy...and... vaccine... development....Along...with... the... recent... increase... in... transplantation... experiments,... the... numbers... of... immunodeficient...animals...have...also...increased....In...addition,...experiments...using...viral...vectors...trend...upward....In...the... context...of...these...circumstances,...it...has...been...required...to...improve...the...animal...breeding...and...research...environment... in...which...each...research...can...coexist... in...the...same...facility....However,...on...the...other...hand,...aging...facilities,... lack...of... breeding...space,...and...efficiency...of...facility...maintenance...have...been...issues...for...many...years....In...order...to...solve...these... problems,...our... facility...has...been...working...on...the... introduction...of...an... individual...ventilation...system...that...can...be... made...into...a...barrier...for...each...cage...from...2019. In... the...BSL2...breeding...room,...where...transplantation...experiments...and...viral...vector...administration...are...mainly... performed,...the...system...has...become...possible...to...significantly...increase...the...number...of...accommodations....We...also... introduced...it...in...the...quarantine...room,...which...previously...used...a...balloon...isolator....This...has...enabled...us...to...introduce... animals...more...efficiency...for...newly...appointed...researchers. In... the...newly...established...rat...breeding...area,... two... types...of... individual...ventilation... systems...were... introduced... according... to... the...purpose...of...production...and...maintenance.... In...addition,... a...bioBUBBLE...system,...which... is... a... prefabricated... clean... room,...was... introduced... for... the... purpose... of...maintaining... the... breeding... of... severely... immunodeficient...rats. In...this...seminar,...we...would... like...to... introduce...the... features,...operation...methods,...problems,...and... future... issues...of... several...newly...introduced...breeding...equipment. Breeding equipment in IMSUT animal facility -Current status and issues-
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