奈及利亚南部尤约市小学生链球菌喉部感染

IF 0.3 Q4 PEDIATRICS
K. Edem, E. Ikpeme, M. Akpan
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引用次数: 0

摘要

摘要监测β-溶血性链球菌(BHS)咽喉感染的携带者状态对疾病控制至关重要。撒哈拉以南非洲最近发表的研究表明,BHS咽喉感染负担的流行病学正在发生变化。因此,本研究的目的是确定阿夸伊博姆州Uyo的学龄儿童中BHS喉咙运输的患病率和模式。本研究是一项前瞻性横断面研究,研究对象为尤约市276名小学生。研究对象采用多阶段随机抽样方法。获得的咽拭子在5%羊血琼脂上培养。使用英国Oxoid Streptococcal grouping Latex Agglutination Kit对阳性培养物进行Lancefield分组。药敏试验采用纸片扩散法。这些关联用费舍尔的精确测试进行了检验。BHS携带率为3.3%。在89%的分离株中鉴定出C组链球菌,在11%的分离株中鉴定出G组链球菌。无症状链球菌咽喉感染与年龄较小和家庭规模较大有关。头孢呋辛和克林霉素的敏感性最高(各占89%),而78%的分离株对青霉素敏感。所有分离株对复方新诺明均不敏感。研究地区链球菌咽部携带的流行率较低。研究地区未发现A群链球菌分离株,提示BHS疾病的流行病学正在演变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Streptococcal Throat Carriage among Primary School Children Living in Uyo, Southern Nigeria
Abstract Surveillance of the carrier state for β-hemolytic streptococcal (BHS) throat infections remains essential for disease control. Recent published works from Sub-Saharan Africa have suggested a changing epidemiology in the burden of BHS throat infections. The objective of the present study was therefore to determine the prevalence and pattern of BHS throat carriage in school-aged children in Uyo, Akwa Ibom State. This was a prospective cross-sectional study of 276 primary school children in Uyo. Subjects were recruited by multistage random sampling. Obtained throat swabs were cultured on 5% sheep blood agar. Lancefield grouping on positive cultures was done by using the Oxoid Streptococcal Grouping Latex Agglutination Kit, United Kingdom. Antimicrobial susceptibility testing was done with the disk diffusion method. Associations were tested with Fischer's exact test. The prevalence of BHS carriage was 3.3%. Group C Streptococcus was identified in 89% of isolates and Group G Streptococcus in 11%. Younger age and larger household size were associated with asymptomatic streptococcal throat infections. Antimicrobial susceptibility was highest with cefuroxime and clindamycin (89% of isolates each), while 78% of isolates were susceptible to penicillin. None of the tested isolates was susceptible to co-trimoxazole. The prevalence of streptococcal throat carriage in the study area was low. There were no Group A Streptococcus isolates suggesting an evolving epidemiology of BHS disease in the study area.
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CiteScore
0.50
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