具有潜伏期和非线性发病率的反应-扩散宿主-病原体模型的定性分析

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Jianpeng Wang, Binxiang Dai
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引用次数: 3

摘要

本文提出了空间异质性环境下具有潜伏期和非线性发病率的简并反应-扩散宿主-病原体模型。我们分析了该模型在有界域上的动力学特性。首先,通过定义一个非紧测度,建立了该问题的适定性,包括解的全局存在性和全局吸引子的存在性。然后给出了基本再现数,并建立了阈值动力学。最后,当存在正稳态时,我们研究了寄主个体以小速率或大速率分散时正稳态的渐近分布。我们的研究结果表明,无论易感宿主或暴露宿主的传播率大小,潜伏期都能显著增强疾病的持久性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Qualitative analysis on a reaction-diffusion host-pathogen model with incubation period and nonlinear incidence rate

In this paper, a degenerate reaction-diffusion host-pathogen model with an incubation period and a nonlinear incidence rate in a spatially heterogeneous environment is proposed. We analyze the dynamics of this model on a bounded domain. Firstly, we establish the well-posedness, including the global existence of solutions and the existence of a global attractor by defining a noncompact measure. Then, the basic reproduction number is given and a threshold dynamics is established. Finally, when there is a positive steady state, we investigate the asymptotic profiles of the positive steady state when host individuals disperse at small or large rate. Our results show that the incubation period can significantly enhance the persistence of the disease if the dispersal rate of susceptible hosts or exposed hosts is small or large.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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