{"title":"具有潜伏期和非线性发病率的反应-扩散宿主-病原体模型的定性分析","authors":"Jianpeng Wang, Binxiang Dai","doi":"10.1016/j.jmaa.2022.126322","DOIUrl":null,"url":null,"abstract":"<div><p>In this paper, a degenerate reaction-diffusion host-pathogen model with an incubation period and a nonlinear incidence rate in a spatially heterogeneous environment is proposed. We analyze the dynamics of this model on a bounded domain. Firstly, we establish the well-posedness, including the global existence of solutions and the existence of a global attractor by defining a noncompact measure. Then, the basic reproduction number is given and a threshold dynamics is established. Finally, when there is a positive steady state, we investigate the asymptotic profiles of the positive steady state when host individuals disperse at small or large rate. Our results show that the incubation period can significantly enhance the persistence of the disease if the dispersal rate of susceptible hosts or exposed hosts is small or large.</p></div>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2022-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Qualitative analysis on a reaction-diffusion host-pathogen model with incubation period and nonlinear incidence rate\",\"authors\":\"Jianpeng Wang, Binxiang Dai\",\"doi\":\"10.1016/j.jmaa.2022.126322\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In this paper, a degenerate reaction-diffusion host-pathogen model with an incubation period and a nonlinear incidence rate in a spatially heterogeneous environment is proposed. We analyze the dynamics of this model on a bounded domain. Firstly, we establish the well-posedness, including the global existence of solutions and the existence of a global attractor by defining a noncompact measure. Then, the basic reproduction number is given and a threshold dynamics is established. Finally, when there is a positive steady state, we investigate the asymptotic profiles of the positive steady state when host individuals disperse at small or large rate. Our results show that the incubation period can significantly enhance the persistence of the disease if the dispersal rate of susceptible hosts or exposed hosts is small or large.</p></div>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2022-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"100\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0022247X22003365\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"100","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0022247X22003365","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Qualitative analysis on a reaction-diffusion host-pathogen model with incubation period and nonlinear incidence rate
In this paper, a degenerate reaction-diffusion host-pathogen model with an incubation period and a nonlinear incidence rate in a spatially heterogeneous environment is proposed. We analyze the dynamics of this model on a bounded domain. Firstly, we establish the well-posedness, including the global existence of solutions and the existence of a global attractor by defining a noncompact measure. Then, the basic reproduction number is given and a threshold dynamics is established. Finally, when there is a positive steady state, we investigate the asymptotic profiles of the positive steady state when host individuals disperse at small or large rate. Our results show that the incubation period can significantly enhance the persistence of the disease if the dispersal rate of susceptible hosts or exposed hosts is small or large.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.