急性a型主动脉夹层修复术围手术期结果不受COVID-19检测延迟的影响

Felix Orelaru, Elizabeth L. Norton, Rana-Armaghan Ahmad, Aroma Naeem, Karen M Kim, S. Fukuhara, H. Patel, G. Deeb, Bo Yang
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摘要

背景:本研究评估了COVID-19检测延迟对单个机构急性A型主动脉夹层(ATAAD)修复围手术期结局的影响。方法:2010年1月至2021年5月,539例ATAAD患者在我院接受了开放式主动脉修复术。其中65例患者在COVID期间(2020年3月至2021年5月)进行了主动脉开腹修复,474例患者在COVID前(2010年1月至2020年2月)。结果:与前冠组相比,新冠期间患者既往心肌缺血比例[9/65 (14%)vs 28/474 (5.9%), p=0.03],慢性阻塞性肺疾病[14/65 (22%)vs 55/474 (12%), p=0.02],肾灌注不良综合征[11/65 (17%)vs 30/474 (6.4%), p=0.01]。两组手术结果无显著差异,包括手术死亡率(7.6% vs 9.2%, p=0.64)。新冠肺炎组入院至手术室(OR)时间中位数为107分钟,而新冠肺炎前组为87分钟,p=0.88。在COVID期间,等待组的中位入院时间比非等待组明显更长(209分钟vs 75分钟,p=0.0009)。只有1例患者的COVID检测呈阳性。在等待COVID检测结果期间,没有主动脉破裂。During-COVID组共报告死亡6例,其中1例死于术后因COVID引起的ARDS, 3例死于缺血性脑卒中,2例死于器官衰竭。结论:ATAAD患者在冠状病毒感染期间的围手术期预后与冠状病毒感染前相似。等待COVID检测结果对修复后ATAAD患者围手术期结局无显著影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perioperative Outcomes of Acute Type-A Aortic Dissection Repair was Unaffected by COVID-19 Testing Delay
Background: This study assesses impact of COVID-19 testing delay on perioperative outcomes of Acute Type A Aortic Dissection (ATAAD) repair at a single institution. Methods: From January 2010 – May 2021, 539 ATAAD patients underwent open aortic repair at our institution. Sixty-five of these patients had open aortic repair during COVID (March 2020 – May 2021) and 474 patients were pre-COVID (January 2010 – February 2020). Results: Compared to the pre-COVID group, patients During-COVID had a higher proportion of previous myocardial ischemia [9/65 (14%) vs 28/474 (5.9%), p=0.03], chronic obstructive pulmonary disease [14/65 (22%) vs 55/474 (12%), p=0.02], and renal malperfusion syndrome [11/65 (17%) vs 30/474 (6.4%), p=0.01]. There was no significant difference in surgical outcomes between groups, including operative mortality (7.6% vs 9.2%, p=0.64). The median admission-to-Operating Room (OR) time was 107 minutes in the During-COVID group compared to 87 minutes in pre-COVID group, p=0.88. During COVID, the median admission-to-OR time was significantly longer in the Waiting group compared to the No-waiting group (209 min vs 75min, p=0.0009). Only one patient had positive COVID test. There were no aortic ruptures while awaiting COVID testing results. There was a total of 6 reported deaths in the During-COVID group: 1 patient died post-surgery due to ARDS caused by COVID, and others due to ischemic stroke (3 patients) and organ failure (2 patients). Conclusions: Perioperative outcomes of ATAAD patients were similar during-COVID compared to pre-COVID. Waiting for COVID testing results did not significantly affect the perioperative outcomes among ATAAD patients after repair.
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