{"title":"可生物降解聚合物微球作为抗菌剂的药物载体","authors":"N. Minocha, Nidhi Bansal, K. Rao, Nikita Yadav","doi":"10.2174/1574885518666230530095329","DOIUrl":null,"url":null,"abstract":"\n\nMicrospheres, the novel drug delivery system that offers therapeutic alternatives to single-unit dosage forms, both conventional and quick release. Microspheres are solid microspheres having a diameter of 1–1000 µm. Microspheres can be made utilising various procedures that\nvary in their effectiveness and dosage form administration when compared to standard dosage forms.\n\n\n\nThe idea of targeted drug delivery is to concentrate the treatment in the target tissues\nwhile lowering the relative concentration of the drug in the non-target tissues. As a result, the medication is concentrated at the desired location. Thus, the medication has no effect on the tissues nearby.\nTherefore, by combining the drug with carrier particle like microspheres, nanoparticles, liposomes, niosomes, etc., that regulates the release and absorption characteristics of the drug, carrier technology\noffers an intelligent way for drug delivery.\n\n\n\nMicrospheres are naturally biodegradable materials made of proteins or synthetic polymers\nthat flow freely. Its formulation is approachable, maintaining the desired concentration at the site of\ninterest without unfavorable effects and reliably delivering the drug to the target site with specificity.\n\n\n\nMicrospheres attracted a lot of interest for their sustained release as well as their ability\nto direct anti-cancer medications to the tumour using biodegradable polymers. Due to this, future drug\ndelivery systems for innovative medications will heavily rely on microspheres.\n","PeriodicalId":11004,"journal":{"name":"Current Drug Therapy","volume":" ","pages":""},"PeriodicalIF":0.3000,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biodegradable Polymeric Microspheres As Drug Carriers For AntiMicrobial Agent\",\"authors\":\"N. Minocha, Nidhi Bansal, K. Rao, Nikita Yadav\",\"doi\":\"10.2174/1574885518666230530095329\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nMicrospheres, the novel drug delivery system that offers therapeutic alternatives to single-unit dosage forms, both conventional and quick release. Microspheres are solid microspheres having a diameter of 1–1000 µm. Microspheres can be made utilising various procedures that\\nvary in their effectiveness and dosage form administration when compared to standard dosage forms.\\n\\n\\n\\nThe idea of targeted drug delivery is to concentrate the treatment in the target tissues\\nwhile lowering the relative concentration of the drug in the non-target tissues. As a result, the medication is concentrated at the desired location. Thus, the medication has no effect on the tissues nearby.\\nTherefore, by combining the drug with carrier particle like microspheres, nanoparticles, liposomes, niosomes, etc., that regulates the release and absorption characteristics of the drug, carrier technology\\noffers an intelligent way for drug delivery.\\n\\n\\n\\nMicrospheres are naturally biodegradable materials made of proteins or synthetic polymers\\nthat flow freely. Its formulation is approachable, maintaining the desired concentration at the site of\\ninterest without unfavorable effects and reliably delivering the drug to the target site with specificity.\\n\\n\\n\\nMicrospheres attracted a lot of interest for their sustained release as well as their ability\\nto direct anti-cancer medications to the tumour using biodegradable polymers. Due to this, future drug\\ndelivery systems for innovative medications will heavily rely on microspheres.\\n\",\"PeriodicalId\":11004,\"journal\":{\"name\":\"Current Drug Therapy\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2023-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Drug Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1574885518666230530095329\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Drug Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1574885518666230530095329","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Biodegradable Polymeric Microspheres As Drug Carriers For AntiMicrobial Agent
Microspheres, the novel drug delivery system that offers therapeutic alternatives to single-unit dosage forms, both conventional and quick release. Microspheres are solid microspheres having a diameter of 1–1000 µm. Microspheres can be made utilising various procedures that
vary in their effectiveness and dosage form administration when compared to standard dosage forms.
The idea of targeted drug delivery is to concentrate the treatment in the target tissues
while lowering the relative concentration of the drug in the non-target tissues. As a result, the medication is concentrated at the desired location. Thus, the medication has no effect on the tissues nearby.
Therefore, by combining the drug with carrier particle like microspheres, nanoparticles, liposomes, niosomes, etc., that regulates the release and absorption characteristics of the drug, carrier technology
offers an intelligent way for drug delivery.
Microspheres are naturally biodegradable materials made of proteins or synthetic polymers
that flow freely. Its formulation is approachable, maintaining the desired concentration at the site of
interest without unfavorable effects and reliably delivering the drug to the target site with specificity.
Microspheres attracted a lot of interest for their sustained release as well as their ability
to direct anti-cancer medications to the tumour using biodegradable polymers. Due to this, future drug
delivery systems for innovative medications will heavily rely on microspheres.
期刊介绍:
Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.