血浆纤维蛋白原作为稳定和加重慢性阻塞性肺疾病的生物标志物

Q3 Medicine

Open Biomarkers Journal Pub Date : 2021-06-10 DOI:10.2174/1875318302111010048

Kashifa Ehsan, S. Zulfiqar, Amber Hassan, H. Waseem

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引用次数: 0

摘要

背景:慢性阻塞性肺疾病(COPD)是一种可预防和可治疗的疾病，但它是一种以气道阻塞为特征的部分可逆性慢性炎症。慢性阻塞性肺病的诊断和治疗仍然不足，因为目前唯一可用的诊断方法是通过肺活量测定法检测肺功能，这无助于确定疾病的严重程度和临床结果。在世界范围内，循环生物标志物正在被考虑用于各种疾病。血浆纤维蛋白原正成为吸烟者COPD最有希望的生物标志物之一。

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Plasma Fibrinogen as a Biomarker of Stable and Exacerbated Chronic Obstructive Pulmonary Disease

Background: Chronic Obstructive Pulmonary Disease (COPD) is a preventable and treatable disease, but is a partially reversible chronic inflammatory condition characterized by airway obstruction. COPD remains under-diagnosed and under-treated because the only available diagnostic method at present is testing lung functions by spirometry which is not helpful to determine the severity and clinical outcomes of the disease. Circulating biomarkers are under consideration for various diseases worldwide. Plasma fibrinogen is emerging as one of the most promising biomarkers of COPD in smokers.

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来源期刊

Open Biomarkers Journal Medicine-Medicine (miscellaneous)

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Open Biomarkers Journal is an Open Access online journal, which publishes original full-length, short research articles and reviews on biomarkers in clinical, medical and pharmaceutical research. The coverage includes biomarkers of disease, new biomarkers, exposure to drugs, genetic effects, and applications of biomarkers. The Open Biomarkers Journal, a peer reviewed journal, aims to provide the most complete and reliable source of information on current developments in the field. The emphasis will be on publishing quality articles rapidly and freely available to researchers worldwide.