文拉法辛XR，高剂量临床应用（>150 mg）

Q4 Medicine

Psychiatria Pub Date : 2020-05-30 DOI:10.5603/psych.2020.0014

Paweł Mierzejewski

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引用次数: 0

摘要

本文讨论了文拉法辛的5 -羟色胺能-去甲肾上腺素能双重作用机制、使用适应症和剂量。特别注意高剂量药物的临床应用，在治疗抑郁症和焦虑症中超过150毫克。文拉法辛是最有效的抗抑郁药之一。最大推荐剂量为焦虑症患者每天225毫克，重度抑郁症患者每天375毫克。使用更高剂量的药物可以充分利用其双重作用机制并提高其有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Wenlafaksyna XR, zastosowanie kliniczne większych dawek (> 150 mg)

This paper discusses the dual serotonergic-noradrenergic mechanism of action of venlafaxine, its indications for use, and dosage. Special attention was paid to the clinical application of higher doses of the drug, above 150 mg in the treatment of depression and anxiety disorders. Venlafaxine is one of the most effective antidepressants. The maximum recommended dose is 225 mg/day for anxiety disorders and 375 mg/day for major depression. The use of higher doses of the drug allows to take full advantage of its dual mechanism of action and improve its effectiveness.

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来源期刊

Psychiatria Medicine-Psychiatry and Mental Health

CiteScore

0.60

自引率

0.00%

发文量

期刊介绍： "Psychiatry" is a quaternary journal addressed to professionals coming from all branches of psychiatry practicing in both hospital and outpatients departments. "Psychiatry" issues original articles, reviews, case reports, commentaries, and translated articles from leading journals in the field of psychiatry. The papers are reviewed by the members of the editorial board. "Psychiatry" also publishes the practice guidelines in sexology. Psychopharmacotherapy is the main field of interests of the quatrernary.