唾液微小RNA（miRNA）在口腔癌症中的表达及其作为生物标志物的意义

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2022-10-01 DOI:10.4103/jiaomr.jiaomr_172_22

Jimsha Kumaran, V. Ramesh, M. Daniel

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引用次数: 0

摘要

口腔癌症是亚洲国家的一个主要公共卫生问题，仅印度就占全球发病率的34%。口腔鳞状细胞癌（SCC）是最常见的。在癌症的发展和进展过程中，致癌是一个复杂的过程。口腔癌症诊断延误仍然是高发病率和高死亡率的主要原因之一。液体活检等非侵入性方法正在被探索为口腔癌症患者体液中的生物标志物。被称为微小RNA（miRNA）的小的非编码RNA调节基因表达，这在癌症的发病机制中起着重要作用。这一简短的交流进一步启发了miRNA的知识及其对口腔癌症的影响。

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Salivary micrornas (miRNAs) expression and its implications as biomarkers in oral cancer

Oral cancer is a major public health concern in Asian countries, with India alone contributing 34% of the global incidence. Oral squamous cell carcinoma (SCC) is the most common. Carcinogenesis is a complex process in the development and progression of cancer. Delay in oral cancer diagnosis remains one of the major causes of high morbidity and mortality. Non-invasive methods such as liquid biopsy are being explored as biomarkers in the body fluid of individuals affected by oral cancer. Small non-coding RNAs called microRNAs (miRNAs) regulate gene expression, which plays an important role in the pathogenesis of cancer. This short communication further enlightens the knowledge of miRNA and its implications for oral cancer.

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来源期刊

Journal of Indian Academy of Oral Medicine and Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

32 weeks

期刊介绍： Journal of Indian Academy of Oral Medicine and Radiology (JIAOMR) (ISSN: Print - 0972-1363, Online - 0975-1572), an official publication of the Indian Academy of Oral Medicine and Radiology (IAOMR), is a peer-reviewed journal, published Quarterly , both in the form of hard copies (print version) as well as on the web (electronic version). The journal’s full text is available online at http://www.jiaomr.in. The journal allows free access (open access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository.