人类基因组计划的余波:一个斗争和发现的时代

IF 1.1 4区 生物学 Q3 BIOLOGY
Zainab Hamdoun, Hashimul Ehsan
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引用次数: 4

摘要

人类基因组计划和桑格研究所在当代赛莱拉基因组学的推动下,在人类基因组测序的竞赛中进行了合作,为新一代研究核酸手册打开了大门。在这一重大成就之后,基因组时代诞生了,预示着基因治疗、个性化医学、药物基因组学和CRISPR/Cas9基因编辑系统的发展。这些“经济学”学科在治疗疾病和改善人类生活质量方面提供了广泛的应用。然而,它们的知名度体现在随后社会学和科学话语的独特组合中。当前基因组时代的里程碑提供了一个独特的机会,可以从深思熟虑的角度看待科学进步,将发现、历史和伦理问题结合在一起,同时鼓励公众以与人类基因组计划开拓者一样的好奇心和热情来考虑这一科学进化的各个方面。把它看作是一种邀请,让我们反思基因组时代的成果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aftermath of the Human Genome Project: an era of struggle and discovery
The collaboration between the Human Genome Project and the Sanger Institute, spurred on by their contemporary- Celera Genomics, in the race to sequence the human genome, opened the door to a generation of research concerned with the study of the nucleic manual. Following this monumental achievement, the genomic era was born, heralding the development of gene therapy, personalized medicine, pharmacogenomics, and CRISPR/Cas9 gene-editing systems. These 'omic' disciplines offer a wide range of applications in the treatment of disease and the betterment of the quality of human life. Their notability, however, manifests in the unique mix of sociological and scientific discourse that ensues. Current genomic-era milestones present a unique opportunity to view scientific advance in a thoughtful light, lacing together discoveries, history, and ethical questions, while encouraging the public to consider the varied facets of this scientific evolution with the same curiosity and enthusiasm as the trailblazers of the Human Genome Project. Consider it an invitation to reflect on the fruits of the genomic era.
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来源期刊
CiteScore
4.60
自引率
0.00%
发文量
20
审稿时长
6-12 weeks
期刊介绍: The Turkish Journal of Biology is published electronically 6 times a year by the Scientific and Technological Research Council of Turkey (TÜBİTAK) and accepts English-language manuscripts concerning all kinds of biological processes including biochemistry and biosynthesis, physiology and metabolism, molecular genetics, molecular biology, genomics, proteomics, molecular farming, biotechnology/genetic transformation, nanobiotechnology, bioinformatics and systems biology, cell and developmental biology, stem cell biology, and reproductive biology. Contribution is open to researchers of all nationalities.
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