{"title":"维生素D在儿童炎症性肠病中的作用","authors":"A. Vernon-Roberts, A. Day","doi":"10.21926/rpn.2202013","DOIUrl":null,"url":null,"abstract":"Children with inflammatory bowel disease (IBD) have a high prevalence of vitamin D insufficiency secondary to factors such as malabsorption and decreased intake. In recent years the benefits of optimal vitamin D status have been highlighted for their potential to improve the disease course and long-term outcomes in this population. Clinical benefits have been seen to bone health, the immune system, and gut health, with further improvements to disease and treatment outcomes. Recommendations for vitamin D treatment parameters to optimize these benefits have been developed, as well as the identification of risk factors for insufficiency specific to children with IBD. While various supplementation regimens are available reports of efficacy are inconsistent, as are guidelines for frequency of testing. Further research is required to elucidate whether hypovitaminosis D is a cause or consequence of IBD, and the role of vitamin D supplementation in treatment warrants significant attention.","PeriodicalId":74647,"journal":{"name":"Recent progress in nutrition","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Role of Vitamin D for Children with Inflammatory Bowel Disease\",\"authors\":\"A. Vernon-Roberts, A. Day\",\"doi\":\"10.21926/rpn.2202013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Children with inflammatory bowel disease (IBD) have a high prevalence of vitamin D insufficiency secondary to factors such as malabsorption and decreased intake. In recent years the benefits of optimal vitamin D status have been highlighted for their potential to improve the disease course and long-term outcomes in this population. Clinical benefits have been seen to bone health, the immune system, and gut health, with further improvements to disease and treatment outcomes. Recommendations for vitamin D treatment parameters to optimize these benefits have been developed, as well as the identification of risk factors for insufficiency specific to children with IBD. While various supplementation regimens are available reports of efficacy are inconsistent, as are guidelines for frequency of testing. Further research is required to elucidate whether hypovitaminosis D is a cause or consequence of IBD, and the role of vitamin D supplementation in treatment warrants significant attention.\",\"PeriodicalId\":74647,\"journal\":{\"name\":\"Recent progress in nutrition\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Recent progress in nutrition\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21926/rpn.2202013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Recent progress in nutrition","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21926/rpn.2202013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Role of Vitamin D for Children with Inflammatory Bowel Disease
Children with inflammatory bowel disease (IBD) have a high prevalence of vitamin D insufficiency secondary to factors such as malabsorption and decreased intake. In recent years the benefits of optimal vitamin D status have been highlighted for their potential to improve the disease course and long-term outcomes in this population. Clinical benefits have been seen to bone health, the immune system, and gut health, with further improvements to disease and treatment outcomes. Recommendations for vitamin D treatment parameters to optimize these benefits have been developed, as well as the identification of risk factors for insufficiency specific to children with IBD. While various supplementation regimens are available reports of efficacy are inconsistent, as are guidelines for frequency of testing. Further research is required to elucidate whether hypovitaminosis D is a cause or consequence of IBD, and the role of vitamin D supplementation in treatment warrants significant attention.