伪装成坏疽的系统性红斑狼疮-罕见的表现

IF 0.2 Q4 DERMATOLOGY
Aditi Singh
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引用次数: 0

摘要

系统性红斑狼疮(SLE)是一种影响多器官的自身免疫性疾病。在皮肤特征中,指坏疽被认为是非常罕见的,仅发生在1.3%的SLE患者中。它被认为是由于继发于血管炎、血管痉挛和血栓栓塞的手指灌注受损。这是一名35岁女性的病例报告,她表现为双足脚趾急性发黑并伴有疼痛。她没有SLE的其他特征。但血清学显示SLE阳性。患者对类固醇、羟氯喹、抗血小板和抗凝药物反应良好,目前正在随访中。这个病例报告基本上告诉我们,当有一个年轻的病人没有任何其他病史,表现为指性坏疽时,SLE应该被认为是一个可能的鉴别诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Systemic lupus erythematosus masquerading as gangrene - an infrequent presentation
Systemic lupus erythematosus (SLE) is an auto-immune disease affecting multiple organs. Among the cutaneous features, digital gangrene is considered to be very rare, occurring in only 1.3% of SLE patients. It is considered to be due to compromised perfusion of digits secondary to vasculitis, vasospasm and thomboembolism. This is the case report of a 35-year-old female who presented with acute blackish discoloration of toes of both feet associated with pain. She had no other features of SLE. But serology came out positive for SLE. The patient responded well to steroids, hydroxychloroquine, antiplatelet and anticoagulant medications and is currently under follow-up. This case report basically shows us that SLE should be considered as a possible differential diagnosis whenever there is a young patient presenting with digital gangrene without any other medical history.
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