长期阿苯达唑治疗免疫功能正常患者弥漫性实质性神经囊虫病1例

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-02-01 DOI:10.4103/1995-7645.368014

Paulus Sugianto, A. Machin, W. Islamiyah, Cindy Cecilia

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引用次数: 0

摘要

理由：脑囊虫病是一种被忽视的热带疾病，由猪带绦虫幼虫引起，可能发生在免疫能力强的人群中。我们报告了一例免疫功能正常患者的弥漫性实质性脑囊虫病，类似结核性脑膜炎。患者关注：一名24岁的免疫活性女性出现一系列局灶性全身性癫痫发作、左侧身体无力、左侧外展神经麻痹、慢性咳嗽和体重减轻。她来自一个她不太可能接触到猪带绦虫的地区。诊断：弥漫性实质性脑囊虫病。干预：丙戊酸、地塞米松和阿苯达唑治疗15个月。结果：完全康复，无任何神经后遗症。经验教训：长期驱虫治疗可能有利于患有多发性脑实质病变的脑囊虫病患者。

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Long-term albendazole therapy for diffuse parenchymal neurocysticercosis in an immunocompetent patient: A case report

Rationale: Neurocysticercosis is a neglected tropical disease caused by the larvae of Taenia solium and may occur in immunocompetent people. We report a case of diffuse parenchymal neurocysticercosis mimicking tuberculous meningitis in an immunocompetent patient. Patient concerns: A 24-year-old immunocompetent woman presented with serial focal to generalized seizure, left body weakness, left abducens palsy, chronic cough, and body weight loss. She came from an area where she was unlikely to have contact with Taenia solium. Diagnosis: Diffuse parenchymal neurocysticercosis. Intervention: Valproic acid, dexamethasone and 15 months of albendazole therapy. Outcome: Complete recovery without any neurological sequelae. Lessons: Prolonged anthelminthic treatment may benefit neurocysticercosis patients with multiple cerebral parenchymal lesions.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.