未分化结缔组织发育不良在非外伤性蛛网膜下腔出血发生及临床中的作用

Shchepankevich La
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引用次数: 0

摘要

近年来的一些研究描述了脑血管的变化,弹性动脉壁的特发性扩张伴随动脉瘤的形成、病理性扭结、环的形成[1-3],这是系统性发育异常过程的表现。评估未分化结缔组织发育不良(UCTD)的临床表现有助于早期诊断,确定蛛网膜下腔出血(SAH)的特征和预后,并确定进一步的正确管理和预防措施[1,4,5]。结缔组织是一种为身体其他器官和组织提供结构和代谢支持的基本组织。与其他组织相比,它的不同之处在于它由分散在细胞外基质中的细胞、纤维和血管组成。遗传性结缔组织疾病是人类最常见的遗传性疾病之一。然而,未分化结缔组织发育不良并不总是在脑血管病变患者中检测到,尤其是非创伤性蛛网膜下腔出血患者[4,5]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Role of Undifferentiated Connective Tissue Dysplasia in the Development and Clinic of Non-Traumatic Subarachnoid Hemorrhage
Some researches of recent years have described the changes in cerebral vessels with idiopathic expansion of the wall of elastic arteries with the formation of an aneurysm, pathological kinking, loop formation [1-3], as a manifestation of a systemic dysplastic process. Assessments of the clinical manifestations of undifferentiated connective tissue dysplasia (UCTD) can help for early diagnosis with the definition of the characteristics and prognosis of the subarachnoid hemorrhage (SAH) with the definition of further correct management and preventive measures [1,4, 5]. The connective tissue is a basic sort of tissue providing structural and metabolic support for other organs and tissues the body. It is different, compared to other tissues, consists in its composition of a diverse set of components cells, fibers, blood vessels scattered throughout the extracellular matrix. Hereditary connective tissue diseases are among the most common human genetic diseases. However, undifferentiated connective tissue dysplasia is not always detected in persons with cerebrovascular pathology, especially with non-traumatic subarachnoid hemorrhage [4, 5].
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