磁颗粒成像在血管成像、免疫治疗、细胞追踪和无创诊断中的应用

IF 2.8 4区医学 Q2 Medicine

Molecular Imaging Pub Date : 2023-03-15 DOI:10.1155/2023/4131117

P. Chandrasekharan, Renesmee Kuo, K. B. Fung, Chinmoy Saayujya, Jacob Bryan, Mariam Yousuf, B. Fellows, Caylin Colson, Q. Huynh, Owen N. Doyle, Allison Hartley, Khadija Yousuf, P. Goodwill, S. Conolly

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引用次数: 1

摘要

磁颗粒成像(MPI)是一种新型的基于示踪剂的成像方式，可用于诊断与血管系统相关的各种病理生理以及对细胞治疗的敏感跟踪。MPI使用无放射性和易于吸收的纳米级氧化铁颗粒作为示踪剂。MPI成像氧化铁颗粒的非线性朗之万行为，并允许对体内氧化铁标记的治疗细胞进行敏感检测。本文将对MPI技术、示踪剂及其在血管成像和分子靶点细胞治疗中的应用进行综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Magnetic Particle Imaging in Vascular Imaging, Immunotherapy, Cell Tracking, and Noninvasive Diagnosis

Magnetic particle imaging (MPI) is a new tracer-based imaging modality that is useful in diagnosing various pathophysiology related to the vascular system and for sensitive tracking of cytotherapies. MPI uses nonradioactive and easily assimilated nanometer-sized iron oxide particles as tracers. MPI images the nonlinear Langevin behavior of the iron oxide particles and has allowed for the sensitive detection of iron oxide-labeled therapeutic cells in the body. This review will provide an overview of MPI technology, the tracer, and its use in vascular imaging and cytotherapies using molecular targets.

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来源期刊

Molecular Imaging 生物-核医学

CiteScore

4.50

自引率

3.60%

发文量

审稿时长

>12 weeks

期刊介绍： Molecular Imaging is a peer-reviewed, open access journal highlighting the breadth of molecular imaging research from basic science to preclinical studies to human applications. This serves both the scientific and clinical communities by disseminating novel results and concepts relevant to the biological study of normal and disease processes in both basic and translational studies ranging from mice to humans.