Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) after Influenza Vaccine followed by a Facial Palsy: Case Report

Purpose: This report describes a case of APMPPE after an Influenza vaccine in an adult and followed by a facial palsy. Methods: A 25-year-old man was admitted to the ophthalmology department because of painless blurred vision on the right eye over two weeks. The patient worked as a soldier and the symptoms started three weeks after having a seasonal anti-flu immunization. The medical chart review and the ancillary investigation disclosed the cause of the visual impairment. Results: The patient was treated with prednisolone 100 mg intravenous. After three months the patient had also a facial palsy. Therefore, we did a cerebral Magnetic Resonance Imaging (MRI). There were no pathological findings. Conclusions: Previous case reports already suggested a possible relationship between various immunizations and APMPPE onset. More studies are required to link APMPPE occurrence and vaccination and disclose the relationship and the risk. *Corresponding author: Marwan Al-Ithawi, Templin Eye Day Clinic, Templin, Germany Check for updates