中国果蔬摄入与动脉高压风险的前瞻性队列研究

Q1 Medicine
Zhi He, Yanhui Jia, Jianxin Li, Jie Cao, Fangchao Liu, Hongfan Li, Jichun Chen, Dongsheng Hu, Chong Shen, Yingxin Zhao, Xiaoqing Liu, Ling Yu, Jianfeng Huang, Xiangfeng Lu, Dongfeng Gu, Shufeng Chen
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引用次数: 0

摘要

背景:关于水果和蔬菜摄入与高血压发病率之间关系的基于人群的流行病学证据是不一致的。这项前瞻性队列研究旨在调查水果和蔬菜摄入与新发高血压风险之间的关系。方法:根据中国动脉粥样硬化性心血管疾病风险预测项目(China-PAR),纳入58981名基线无高血压的中国成年人。有关水果和蔬菜摄入量的信息是使用食物频率问卷收集的。采用Cox比例风险模型来估计偶发高血压的风险比(HR)和95%置信区间(CI)。结果:在640795人年的随访中,记录了21008例新的高血压病例。与水果和蔬菜总摄入量最低五分之一(Q1)的参与者相比,Q2至Q5组发生高血压的HR(95%CI)分别为0.90(0.86-0.95)、0.85(0.81-0.90)、0.82(0.78-0.86)和0.83(0.78-8.88)(p趋势 结论:这些结果表明,增加水果和蔬菜的摄入量有利于预防中国成年人的高血压。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Fruit and vegetable intake and the risk of arterial hypertension in China: A prospective cohort study

Fruit and vegetable intake and the risk of arterial hypertension in China: A prospective cohort study

Background

Population-based epidemiological evidence regarding the association between fruit and vegetable intake and the incidence of hypertension is inconsistent. This prospective cohort study aimed to investigate the association between fruit and vegetable intake and the risk of new-onset hypertension.

Methods

Based on the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR), 58,981 Chinese adults without hypertension at baseline were included. Information on fruit and vegetable intake was collected using a food-frequency questionnaire. Cox proportional hazards models were performed to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) of incident hypertension.

Results

During 640,795 person-years of follow-up, 21,008 new cases of hypertension were recorded. Compared with participants in the lowest quintile (Q1) of total fruit and vegetable (TFV) intake, the HRs (95% CIs) of incident hypertension were 0.90 (0.86–0.95), 0.85 (0.81–0.90), 0.82 (0.78–0.86), and 0.83 (0.78–0.88) for the Q2 to Q5 group (ptrend < 0.001), respectively. In further analyses categorizing participants according to the recommended intake level (500 g/day), we found that increasing the intake of TFV, even though it was still insufficient for the recommendation, also had a protective effect against the incident hypertension. When considering the intake of fruit or vegetable separately, we found similar trends as the TFV intake.

Conclusion

These results suggest that a higher intake of fruit and vegetable is beneficial for preventing hypertension in Chinese adults.

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来源期刊
CiteScore
6.70
自引率
0.00%
发文量
195
审稿时长
35 weeks
期刊介绍: This journal aims to promote progress from basic research to clinical practice and to provide a forum for communication among basic, translational, and clinical research practitioners and physicians from all relevant disciplines. Chronic diseases such as cardiovascular diseases, cancer, diabetes, stroke, chronic respiratory diseases (such as asthma and COPD), chronic kidney diseases, and related translational research. Topics of interest for Chronic Diseases and Translational Medicine include Research and commentary on models of chronic diseases with significant implications for disease diagnosis and treatment Investigative studies of human biology with an emphasis on disease Perspectives and reviews on research topics that discuss the implications of findings from the viewpoints of basic science and clinical practic.
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