西红花提取物对癌症MCF-7细胞的抑制作用

Q4 Pharmacology, Toxicology and Pharmaceutics

Iranian Journal of Toxicology Pub Date : 2021-01-10 DOI:10.32598/IJT.15.1.752.1

Bhenaz Hatefi Kia, Sakineh Kazemi Noureini, M. R. Vaezi Kakhki

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引用次数: 5

摘要

方法:采集该植物的根、地上部分和花，在常温下避光干燥。制备各部位的水提物和甲醇提物。采用MTT法观察各提取物对MCF-7乳腺癌细胞和HEK293正常细胞株生长的影响。每个实验至少独立重复三次。对各治疗时间点的IC50值进行分析，采用方差分析，P<0.05。

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The Extracts of Epilobium Parviflorum Inhibit MCF-7 Breast Cancer Cells

Methods: The root, aerial parts and flowers of the plant were, collected and dried separately at ambient temperature and away from direct sunlight. The aquatic and methanolic extracts of each part was prepared. The effect of each extract on the growth of MCF-7 breast carcinoma cells and HEK293 normal cell line was evaluated, using MTT assay. Each experiment was repeated at least three times independently. The IC50 values for each treatment time point were analyzed, using ANOVA at P<0.05.

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来源期刊

Iranian Journal of Toxicology Environmental Science-Health, Toxicology and Mutagenesis

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

9 weeks