冲入效应及其对大规模伤亡净化的意义

IF 6.4 2区医学 Q1 ENVIRONMENTAL SCIENCES

Journal of Toxicology and Environmental Health-Part B-Critical Reviews Pub Date : 2022-02-27 DOI:10.1080/10937404.2022.2042443

Thomas James, Lydia Izon-Cooper, S. Collins, Haydn Cole, T. Marczylo

{"title":"冲入效应及其对大规模伤亡净化的意义","authors":"Thomas James, Lydia Izon-Cooper, S. Collins, Haydn Cole, T. Marczylo","doi":"10.1080/10937404.2022.2042443","DOIUrl":null,"url":null,"abstract":"ABSTRACT Decontamination of skin by washing may increase dermal absorption, a phenomenon known as the wash-in effect. The wash-in effect is frequently discussed in studies investigating casualty decontamination where potentially life-saving interventions may enhance the dermal penetration of toxic chemicals, leading to an increase in incidence of morbidity and rates of mortality. However, the wash-in effect is seldom investigated within the context of mass casualty decontamination and real-life consequences are therefore poorly understood. This paper reviews the existing literature on the wash-in effect to highlight the proposed mechanisms for enhanced absorption and evaluate the wash-in effect within the context of mass casualty chemical decontamination.","PeriodicalId":49971,"journal":{"name":"Journal of Toxicology and Environmental Health-Part B-Critical Reviews","volume":"25 1","pages":"113 - 134"},"PeriodicalIF":6.4000,"publicationDate":"2022-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"The wash-in effect and its significance for mass casualty decontamination\",\"authors\":\"Thomas James, Lydia Izon-Cooper, S. Collins, Haydn Cole, T. Marczylo\",\"doi\":\"10.1080/10937404.2022.2042443\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABSTRACT Decontamination of skin by washing may increase dermal absorption, a phenomenon known as the wash-in effect. The wash-in effect is frequently discussed in studies investigating casualty decontamination where potentially life-saving interventions may enhance the dermal penetration of toxic chemicals, leading to an increase in incidence of morbidity and rates of mortality. However, the wash-in effect is seldom investigated within the context of mass casualty decontamination and real-life consequences are therefore poorly understood. This paper reviews the existing literature on the wash-in effect to highlight the proposed mechanisms for enhanced absorption and evaluate the wash-in effect within the context of mass casualty chemical decontamination.\",\"PeriodicalId\":49971,\"journal\":{\"name\":\"Journal of Toxicology and Environmental Health-Part B-Critical Reviews\",\"volume\":\"25 1\",\"pages\":\"113 - 134\"},\"PeriodicalIF\":6.4000,\"publicationDate\":\"2022-02-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Toxicology and Environmental Health-Part B-Critical Reviews\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/10937404.2022.2042443\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Toxicology and Environmental Health-Part B-Critical Reviews","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/10937404.2022.2042443","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 1

摘要

摘要：通过洗涤来净化皮肤可能会增加真皮吸收，这种现象被称为洗涤效果。在调查伤员去污的研究中，经常讨论冲刷效应，其中潜在的救生干预措施可能会增强有毒化学物质的皮肤渗透，导致发病率和死亡率增加。然而，很少在大规模伤亡净化的背景下对冲刷效应进行调查，因此对现实生活中的后果了解甚少。本文回顾了现有的关于冲洗效果的文献，以强调所提出的增强吸收的机制，并在大规模伤亡化学去污的背景下评估冲洗效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The wash-in effect and its significance for mass casualty decontamination

ABSTRACT Decontamination of skin by washing may increase dermal absorption, a phenomenon known as the wash-in effect. The wash-in effect is frequently discussed in studies investigating casualty decontamination where potentially life-saving interventions may enhance the dermal penetration of toxic chemicals, leading to an increase in incidence of morbidity and rates of mortality. However, the wash-in effect is seldom investigated within the context of mass casualty decontamination and real-life consequences are therefore poorly understood. This paper reviews the existing literature on the wash-in effect to highlight the proposed mechanisms for enhanced absorption and evaluate the wash-in effect within the context of mass casualty chemical decontamination.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Toxicology and Environmental Health-Part B-Critical Reviews 环境科学-毒理学

CiteScore

13.80

自引率

6.90%

发文量

审稿时长

>24 weeks

期刊介绍： "Journal of Toxicology and Environmental Health: Part B - Critical Reviews" is an academic journal published by Taylor & Francis, focusing on the critical examination of research in the areas of environmental exposure and population health. With an ISSN identifier of 1093-7404, this journal has established itself as a significant source of scholarly content in the field of toxicology and environmental health. Since its inception, the journal has published over 424 articles that have garnered 35,097 citations, reflecting its impact and relevance in the scientific community. Known for its comprehensive reviews, the journal also goes by the names "Critical Reviews" and "Journal of Toxicology & Environmental Health, Part B, Critical Reviews." The journal's mission is to provide a platform for in-depth analysis and critical discussion of the latest findings in toxicology, environmental health, and related disciplines. By doing so, it contributes to the advancement of knowledge and understanding of the complex interactions between environmental factors and human health, aiding in the development of strategies to protect and improve public health.