阿尔及利亚胸腺的植物化学物质、抗溶血、抗炎、抗氧化和抗菌活性

IF 1.2 Q4 PHARMACOLOGY & PHARMACY

Journal of Herbs, Spices and Medicinal Plants Pub Date : 2021-03-12 DOI:10.1080/10496475.2021.1891174

Mouna Mokhtari, S. Chabani, Soumia Mouffouk, M. Aberkane, A. Dibi, M. Benkhaled, Hamada Haba

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引用次数: 9

摘要

摘要对阿尔及利亚百里香的石油醚、三氯甲烷和正丁醇溶剂提取物的化学组成及其抗炎、镇痛、抗氧化和抗菌活性进行了评价。从中分离得到10个化合物，包括4个黄酮类化合物、4个酚类化合物和2个三萜类化合物。正丁醇提取物具有最大的抗氧化活性并抑制溶血，IC50值为322.85±0.87µg mL−1。氯仿提取物具有最高的抗炎作用，抑制率为45.27%。提取物对试验菌株具有抗菌活性。

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Phytochemicals, Antihemolytic, Anti-inflammatory, Antioxidant, and Antibacterial Activities from Thymus Algeriensis

ABSTRACT The chemical composition and anti-inflammatory, antihemolytic, antioxidant, and antibacterial activities of solvent extracts of Thymus algeriensis in petroleum ether, chloroform, and n-butanol were evaluated. Ten compounds including four flavonoids, four phenolics, and two triterpenoids were isolated and identified by chromatography and spectroscopy. The n-butanol extract had the greatest antioxidant activity and inhibited hemolysis with a value of IC50 at 322.85 ± 0.87 µg mL−1. The chloroform extract exhibited the highest anti-inflammatory effect with 45.27% inhibition. The extracts demonstrated antibacterial activity against the tested strains.

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来源期刊

Journal of Herbs, Spices and Medicinal Plants Medicine-Complementary and Alternative Medicine

CiteScore

3.00

自引率

0.00%

发文量

期刊介绍： The Journal of Herbs, Spices & Medicinal Plants is an essential reference filled with recent research and other valuable information associated with herbs, spices, and medicinal plants. The Journal serves as a focus point through which investigators and others may publish material of importance to the production, marketing, and utilization of these plants and associated extracts. The journal covers the following topics: growth, development, horticulture, ecology, physiology, genetics, chemistry, and economics. Original articles, review articles, and book reviews provide information of interest to an international audience of researchers, teachers, technicians, and managers involved with production and/or marketing of herbs, spices, and medicinal plants. Managers of food companies, food processing facilities, medical research laboratories, government agencies, and others interested in new chemicals, food additives, international trade, patents, and other items can easily review new findings. The Journal of Herbs, Spices & Medicinal Plants is a forum in which recent research and other information associated with herbs, spices, and medicinal plants is shared. The Journal represents a centralized database accessible by investigators within the international community that work with or have an interest in herbs, spices, and medicinal plants.