基于10年肝脏活检样本的新西兰猫肝胆疾病相对频率的回顾性研究

IF 1.3 Q2 VETERINARY SCIENCES
T. Fluen, M. Hardcastle, Helen Smith, R. Gear
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引用次数: 3

摘要

目的从10年内提交给一个实验室的活组织检查样本中,回顾性地确定猫肝胆疾病的相对频率,并确定是否存在年龄、性别或品种关联。方法分析2008年至2018年间采集的154只新西兰猫肝脏活检的组织病理学数据。根据世界小动物兽医协会制定的标准,将样本分为原发性、继发性和三级疾病。使用OR和95%CI得出品种关联。还对性别和年龄关联进行了评估。结果最常见的肝胆疾病是淋巴细胞性胆管炎(20%)、肝炎(16.9%)、可逆性肝细胞损伤(16.4%)、中性粒细胞性胆管管炎(9.7%)、造血细胞瘤变(9.7%。缅甸猫患胆道和实质性疾病的风险显著增加,伯曼猫患实质性疾病风险显著增加。家猫长毛猫患肝胆肿瘤的风险显著增加。Birman猫患肝炎的风险显著增加,而家猫患中性粒细胞性胆管炎、可逆性肝细胞损伤和肝炎的风险明显降低。结论本研究是首次对新西兰猫肝活检标本中肝胆疾病的相对频率进行回顾性检查。一些品种与特定的组织病理学有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Retrospective study of the relative frequency of feline hepatobiliary disease in New Zealand based on 10 years of hepatic biopsy samples
Aims To retrospectively determine the relative frequency of feline hepatobiliary diseases from biopsy specimens submitted to a single laboratory across a 10-year period and to establish whether age, sex or breed associations exist. Methods Histopathological data from 154 liver biopsies of New Zealand cats sampled between 2008 and 2018 were analysed. The samples were allocated to primary, secondary and tertiary disease categories using criteria established by the World Small Animal Veterinary Association. Breed associations were derived using ORs and 95% CIs. Gender and age associations were also evaluated. Results The most frequently diagnosed hepatobiliary diseases were lymphocytic cholangitis (20 per cent), hepatitis (16.9 per cent), reversible hepatocellular injury (16.4 per cent), neutrophilic cholangitis (9.7 per cent), haematopoietic neoplasia (9.7 per cent), hepatocellular neoplasia (5.6 per cent) and cholangiocellular neoplasia (4.1 per cent). Burmese cats were found to be at significantly increased risk of both biliary and parenchymal diseases and Birman cats to be at significantly increased risk of parenchymal disease. Domestic longhair cats were at significantly increased risk of hepatobiliary neoplasia. Birman cats were at significantly increased risk of hepatitis while domestic shorthair cats were at significantly decreased risk of neutrophilic cholangitis, reversible hepatocellular injury and hepatitis. Conclusions This study is the first retrospective examination of the relative frequency of hepatobiliary disease in biopsy specimens from New Zealand cats. Some breeds were associated with specific histopathology.
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来源期刊
Veterinary Record Open
Veterinary Record Open VETERINARY SCIENCES-
CiteScore
3.00
自引率
0.00%
发文量
25
审稿时长
19 weeks
期刊介绍: Veterinary Record Open is a journal dedicated to publishing specialist veterinary research across a range of topic areas including those of a more niche and specialist nature to that considered in the weekly Vet Record. Research from all disciplines of veterinary interest will be considered. It is an Open Access journal of the British Veterinary Association.
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