干细胞衍生类器官在肾癌治疗中的局限性和前景

Dylan Monaghan, V. Gallicchio
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引用次数: 0

摘要

肾细胞癌(RCC)是泌尿生殖系统最常见的癌症类型,目前在男性中排名第六,在女性中排名第十。RCC最常在60至70岁的人群中偶然发现,具有高度的异质性和极高的转移风险。最近,已知该疾病包含不同的组织学亚型和独特的遗传和分子修饰,甚至使治疗方案进一步复杂化。疾病的进展可影响消化、骨骼、循环、免疫、神经和生殖系统,引起广泛的症状,包括咳嗽、胸痛和骨痛、恶心、呼吸短促、发烧、癫痫发作等。由于不成功的盛行
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current Limitations And The Future Promise Of Stem Cell-Derived Organoids In Renal Cell Carcinoma Treatment
Renal Cell Carcinoma (RCC) is the most common type of urogenital cancer and is currently ranked as the sixth most common cancer among men and tenth among women. RCC is most often detected incidentally in individuals between the ages of 60 and 70 and possesses a high degree of heterogeneity with an extremely high risk of metastasis. Recently, the disease has become known to encompass differing histological subtypes and unique genetic and molecular modifications, even further complicating treatment options. The progression of the disease can affect the digestive, skeletal, circulatory, immune, nervous, and reproductive systems causing a wide range of symptoms including cough, chest and bone pain, nausea, shortness of breath, fever, seizures, and more. Due to the prevalence of unsuccessful
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