灌注指数预测下段剖宫产术后脊髓性低血压

IF 1.5 Q3 PHARMACOLOGY & PHARMACY
Minal J Harde, Prashant B Ranale, Sarita Fernandes
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引用次数: 0

摘要

背景和目的:预测和预防下段剖宫产术(LSCS)中的椎管后低血压非常重要。外周血管张力可通过脉搏血氧仪监测灌注指数(PI)。我们的目的是研究基线 PI 作为 LSCS 中椎管后低血压的预测因子:一项前瞻性观察研究在一家三级公立教学医院进行,对象是在脊髓麻醉下接受择期 LSCS 的患者。比较了基线 PI 和低血压。绘制了接收者操作特征曲线(ROC),并使用 SPSS 20 版对数据进行了分析:在 90 名女性中,43 人(47.8%)的 PI ≤3.5,47 人(52.2%)的 PI >3.5。在 PI >3.5 组中,46 名女性(97.9%)出现低血压并需要大量静脉输液,29 名女性(61.7%)需要使用血管加压药,与 PI 的关系具有统计学意义,Pearson's Chi-square 值分别为 32.26 和 32.36(P = 0.001)。在 ROC 中,曲线下面积(AUC)为 0.917,证明基线 PI >2.9 是一个很好的分类器(P < 0.0001,95% 置信区间 [CI] 0.840-0.965),可预测低血压,敏感性为 83.08%,特异性为 96.00%:结论:基线PI>3.5与LSCS患者椎管后明显低血压和使用血管加压药有关。我们认为基线 PI >2.9 可以预测椎管后低血压,具有很高的灵敏度和特异性。PI 简单、快速、无创,可用作预测接受 LSCS 的产妇椎管后低血压的指标,以便考虑对高危患者采取预防措施,改善产妇和胎儿的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perfusion index to predict post spinal hypotension in lower segment caesarean section.

Background and aims: It is important to predict and prevent post-spinal hypotension in lower segment cesarean section (LSCS). Peripheral vascular tone can be monitored as a perfusion index (PI) from a pulse oximeter. We aimed to study baseline PI as a predictor of post-spinal hypotension in LSCS.

Material and methods: Prospective observational study conducted in a tertiary care teaching public hospital on patients posted for elective LSCS under spinal anesthesia. Baseline PI and hypotension were compared. A receiver operating characteristic (ROC) curve was plotted and data were analyzed using SPSS version 20.

Results: Among 90 females, 43 (47.8%) had a PI ≤3.5 and 47 (52.2%) had a PI >3.5. In the PI >3.5 group, 46 (97.9%) females had hypotension and required a high volume of IV fluids, and 29 (61.7%) required vasopressors, and the association with PI was statistically significant with Pearson's Chi-square values of 32.26 and 32.36, respectively (P = 0.001). In the ROC, the area under the curve (AUC) was 0.917, proving baseline PI >2.9 as an excellent classifier (P < 0.0001,95% confidence interval [CI] 0.840-0.965) and can predict hypotension with a sensitivity of 83.08% and specificity of 96.00%.

Conclusion: Baseline PI >3.5 was associated with significant post-spinal hypotension and vasopressor administration in LSCS. We established baseline PI >2.9 can predict post-spinal hypotension with high sensitivity and specificity. PI is simple, quick, and non-invasive and can be used as a predictor for post-spinal hypotension in parturients undergoing LSCS so that prophylactic measures can be considered in at-risk patients for better maternal and fetal outcomes.

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来源期刊
CiteScore
1.90
自引率
6.70%
发文量
129
期刊介绍: The JOACP publishes original peer-reviewed research and clinical work in all branches of anaesthesiology, pain, critical care and perioperative medicine including the application to basic sciences. In addition, the journal publishes review articles, special articles, brief communications/reports, case reports, and reports of new equipment, letters to editor, book reviews and obituaries. It is international in scope and comprehensive in coverage.
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