热带爪蟾早期胚胎发育过程中过氧氧化还原素基因家族的发育表达。

IF 1 4区 生物学 Q4 DEVELOPMENTAL BIOLOGY
Linke Zhong , Tingting Fu , Chengdong Wang , Xufeng Qi , Wai-Yee Chan , Dongqing Cai , Hui Zhao
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引用次数: 1

摘要

过氧化物酶基因(Prdx)编码一个抗氧化蛋白家族,可以通过减少各种细胞过氧化物来保护细胞免受氧化损伤。本研究探讨了热带爪蟾早期发育过程中该家族基因成员的时空表达模式。实时定量PCR显示,该基因家族的所有成员在热带X.胚胎的早期发育过程中都有不同的时间表达模式。此外,全支架原位杂交显示,单个prdx基因表现出不同的表达模式,在淋巴管、前肾、近端小管和鳃弓中重叠表达。本研究为进一步研究prdx基因家族的功能提供了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Developmental expression of peroxiredoxin gene family in early embryonic development of Xenopus tropicalis

Peroxidase genes (Prdx) encode a family of antioxidant proteins, which can protect cells from oxidative damage by reducing various cellular peroxides. This study investigated the spatiotemporal expression patterns of gene members in this family during the early development of Xenopus tropicalis. Real-time quantitative PCR showed that all members of this gene family have a distinct temporal expression pattern during the early development of X. tropicalis embryos. Additionally, whole mount in situ hybridization revealed that individual prdx genes display differential expression patterns, with overlapping expression in lymphatic vessels, pronephros, proximal tubule, and branchial arches. This study provides a basis for further study of the function of the prdx gene family.

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来源期刊
Gene Expression Patterns
Gene Expression Patterns 生物-发育生物学
CiteScore
2.30
自引率
0.00%
发文量
42
审稿时长
35 days
期刊介绍: Gene Expression Patterns is devoted to the rapid publication of high quality studies of gene expression in development. Studies using cell culture are also suitable if clearly relevant to development, e.g., analysis of key regulatory genes or of gene sets in the maintenance or differentiation of stem cells. Key areas of interest include: -In-situ studies such as expression patterns of important or interesting genes at all levels, including transcription and protein expression -Temporal studies of large gene sets during development -Transgenic studies to study cell lineage in tissue formation
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