接受计算机断层扫描血管造影术的急性脑卒中患者造影剂诱导肾病的发生率和危险因素：一项单中心研究。

IF 1.2 4区医学 Q4 CLINICAL NEUROLOGY

Neurosciences Pub Date : 2023-10-01 DOI:10.17712/nsj.2023.4.20230030

Muhannad A Asiri, Mohammed S Alqahtani, Saeed A Alqahtani, Mohammed M Alwadai, Naif F Alharbi, Mohammed O Aqeeli, Saeed S Alzahrani

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引用次数: 0

摘要

目的：调查这一特定患者群体中造影剂诱导肾病的患病率和相关风险因素，以确保最高质量的临床护理。方法：在回顾性分析中，所有于2022年3月至11月在吉达法赫德国王医院急诊科出现急性中风并接受计算机断层扫描血管造影（CTA）的患者，纳入标准如下：基线肌酸酐结果和症状出现后24小时内进行的CTA检查以及早期可用（结果：在246名急诊中风患者中，182人接受了脑CTA检查，8.24%患有造影剂诱导肾病（CIN）。脑出血（ICH）使CIN风险增加了7倍（OR=6.7；95%CI:1.23-33.3）。异常基线使CIN危险增加了8倍（OR=7.8；95%CI:1.74-35.1）。高血压使CIN的风险增加了一倍（OR=2.1；95%CI:1.26-6.98）结论：CIN的发生率为8.2%，尤其是在ICH、高血压、组织纤溶酶原给药和异常基线的患者中，在处理急性中风病例时必须保持警惕。

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Incidence and risk factors of contrast-induced nephropathy in acute stroke patients undergoing computed tomography angiography: A single-center study.

Objectives: To investigate the prevalence and risk factors linked to contrast-induced nephropathy in this specific patient population, aiming to ensure the highest quality of clinical care.

Methods: In a retrospective analysis, all patients who presented with an acute stroke to King Fahad Hospital, Jeddah, Emergency Department from March until November 2022 and underwent Computed Tomography Angiography (CTA) brain, Inclusion criteria were as follows: a baseline creatinine results and CTA examination performed within 24 hours of symptom onset and an available early (<5 days after CTA) follow-up creatinine result.

Results: Among 246 stroke patients in the emergency, 182 underwent brain CTA and 8.24% had Contrast-Induced Nephropathy (CIN). intracerebral hemorrhage (ICH) increased CIN risk 7-fold (OR=6.7; 95% CI: 1.23-33.3). Abnormal baseline raised CIN risk 8-fold (OR=7.8; 95% CI: 1.74-35.1). hypertension doubled the risk for CIN (OR=2.1; 95% CI: 1.26-6.98) CONCLUSION: The incidence of CIN was 8.2%, particularly elevated in patients with ICH, hypertension, tissue plasminogen administration, and abnormal baseline, necessitating vigilance in managing acute stroke cases.

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来源期刊

Neurosciences 医学-临床神经学

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

4.5 months

期刊介绍： Neurosciences is an open access, peer-reviewed, quarterly publication. Authors are invited to submit for publication articles reporting original work related to the nervous system, e.g., neurology, neurophysiology, neuroradiology, neurosurgery, neurorehabilitation, neurooncology, neuropsychiatry, and neurogenetics, etc. Basic research withclear clinical implications will also be considered. Review articles of current interest and high standard are welcomed for consideration. Prospective workshould not be backdated. There are also sections for Case Reports, Brief Communication, Correspondence, and medical news items. To promote continuous education, training, and learning, we include Clinical Images and MCQ’s. Highlights of international and regional meetings of interest, and specialized supplements will also be considered. All submissions must conform to the Uniform Requirements.