微极理论框架下的血流建模

IF 1.9 4区 工程技术 Q3 MECHANICS
Anastasiya E. Vilchevskaya, Elena N. Vilchevskaya, Wolfgang H. Müller, Victor A. Eremeyev
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引用次数: 0

摘要

在本文中,我们研究了通过不同半径血管的血流(包括可变横截面的情况以及通过静脉和动脉的血流建模)。讨论了两种方法来模拟血液粘度对红细胞聚集的依赖性,红细胞聚集随剪切速率和血管内位置的变化而变化:提出了两个微观结构参数以及作为聚集特征的经验本构方程,即微量惯量以及血液颗粒(红细胞、血小板和白细胞)的体积分数。因此,不可压缩流体的Navier-Stokes方程组由一种情况下的惯性矩本构方程和另一种情况中的体积分数本构方程补充。在空间描述中,用有限体积法对各种几何形状的容器进行了数值求解。与狭窄毛细管的实验数据的比较表明了所提出的本构方程描述血流的有效性。此外,基于汇编的可变半径血管各截面的经验公式,获得了速度剖面。此外,还研究了人体循环系统血管的流动,如下腔静脉和颈动脉。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Modeling of blood flow in the framework of micropolar theory

Modeling of blood flow in the framework of micropolar theory

In this paper, we study the blood flow through blood vessels of various radii (including the case of variable cross section as well as modeling the blood flow through venae and arteries). Two approaches are discussed in order to mimic the dependence of blood viscosity on red blood cells aggregation, which changes with the shear rate and position inside the vessel: Two microstructural parameters together with empirical constitutive equations as a characteristic of aggregation are proposed, namely the microinertia as well as the volume fraction of blood particles (erythrocytes, platelets and leukocytes). Consequently, the Navier–Stokes system of equations for an incompressible fluid is supplemented by a constitutive equation for the moment of inertia in one case and for the volume fraction in another. The problems are solved numerically by the finite volume method for vessels of various geometries in spatial description. A comparison with experimental data for a narrow capillary shows the efficiency of the proposed constitutive equations for describing blood flow. Also, velocity profiles are obtained on the basis of compiled empirical formula for various sections of a blood vessel of variable radius. In addition, the flow through vessels of the human circulatory system, such as the inferior vena cava and the carotid artery, are studied.

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来源期刊
CiteScore
5.30
自引率
15.40%
发文量
92
审稿时长
>12 weeks
期刊介绍: This interdisciplinary journal provides a forum for presenting new ideas in continuum and quasi-continuum modeling of systems with a large number of degrees of freedom and sufficient complexity to require thermodynamic closure. Major emphasis is placed on papers attempting to bridge the gap between discrete and continuum approaches as well as micro- and macro-scales, by means of homogenization, statistical averaging and other mathematical tools aimed at the judicial elimination of small time and length scales. The journal is particularly interested in contributions focusing on a simultaneous description of complex systems at several disparate scales. Papers presenting and explaining new experimental findings are highly encouraged. The journal welcomes numerical studies aimed at understanding the physical nature of the phenomena. Potential subjects range from boiling and turbulence to plasticity and earthquakes. Studies of fluids and solids with nonlinear and non-local interactions, multiple fields and multi-scale responses, nontrivial dissipative properties and complex dynamics are expected to have a strong presence in the pages of the journal. An incomplete list of featured topics includes: active solids and liquids, nano-scale effects and molecular structure of materials, singularities in fluid and solid mechanics, polymers, elastomers and liquid crystals, rheology, cavitation and fracture, hysteresis and friction, mechanics of solid and liquid phase transformations, composite, porous and granular media, scaling in statics and dynamics, large scale processes and geomechanics, stochastic aspects of mechanics. The journal would also like to attract papers addressing the very foundations of thermodynamics and kinetics of continuum processes. Of special interest are contributions to the emerging areas of biophysics and biomechanics of cells, bones and tissues leading to new continuum and thermodynamical models.
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