免疫细胞在贝氏病中的作用。

IF 2 4区 医学 Q3 RHEUMATOLOGY
Dan Hu, Jian-Long Guan
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引用次数: 0

摘要

Behçet病(BD)是一种系统性血管炎,可影响多个系统,包括皮肤、粘膜、关节、眼睛、胃肠道和神经系统。然而,BD的发病机制尚不清楚,免疫炎症反应在其发展中起着至关重要的作用。免疫细胞是这一过程的关键组成部分,有助于BD的发生和发展。通过调节这些免疫细胞的功能,可以实现对BD发生和发展的有效控制,特别是在单核细胞活化和聚集、巨噬细胞分化和极化以及T细胞亚群分化方面。这篇综述简要介绍了免疫细胞及其在BD进展中的调节作用,这可能为预防和治疗该疾病提供理论基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The roles of immune cells in Behçet's disease.

Behçet's disease (BD) is a systemic vasculitis that can affect multiple systems, including the skin, mucous membranes, joints, eyes, gastrointestinal and nervous. However, the pathogenesis of BD remains unclear, and it is believed that immune-inflammatory reactions play a crucial role in its development. Immune cells are a critical component of this process and contribute to the onset and progression of BD. By regulating the function of these immune cells, effective control over the occurrence and development of BD can be achieved, particularly with regards to monocyte activation and aggregation, macrophage differentiation and polarization, as well as T cell subset differentiation. This review provides a brief overview of immune cells and their role in regulating BD progression, which may serve as a theoretical foundation for preventing and treating this disease.

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来源期刊
Advances in Rheumatology
Advances in Rheumatology Medicine-Rheumatology
CiteScore
4.00
自引率
4.30%
发文量
41
审稿时长
53 weeks
期刊介绍: Formerly named Revista Brasileira de Reumatologia, the journal is celebrating its 60th year of publication. Advances in Rheumatology is an international, open access journal publishing pre-clinical, translational and clinical studies on all aspects of paediatric and adult rheumatic diseases, including degenerative, inflammatory and autoimmune conditions. The journal is the official publication of the Brazilian Society of Rheumatology and welcomes original research (including systematic reviews and meta-analyses), literature reviews, guidelines and letters arising from published material.
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