新冠肺炎大流行期间日本大学生抑郁状态的动态:中断时间序列分析。

IF 3.6 3区 医学 Q1 PSYCHIATRY
N Shiraishi, M Sakata, R Toyomoto, K Yoshida, Y Luo, Y Nakagami, A Tajika, T Watanabe, E Sahker, T Uwatoko, T Shimamoto, T Iwami, T A Furukawa
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引用次数: 0

摘要

背景:据报道,2019冠状病毒病(新冠肺炎)大流行增加了大学生的抑郁症,这与他们的校园生活障碍有关。这项研究调查了新冠肺炎大流行期间日本大学生抑郁状态的变化。方法:对一项基于智能手机的认知行为疗法的析因随机对照试验进行二次数据分析。六个队列(N = 1626)在2019-2021年春季或秋季接受了为期8周的干预,并进行了9个月的随访。在干预期间,我们每周使用患者健康问卷-9(PHQ-9)评估参与者的抑郁状态,此后每月进行评估。随访期间包括日本控制新冠肺炎的四个紧急状态。假设国有企业导致抑郁状态突然恶化,研究1比较了队列的PHQ-9评分,研究2采用时间序列分析和混合效应模型来估计PHQ-9得分的已确定变化。结果:尽管没有观察到与SOE相关的抑郁状态变化,但研究1发现,在28周的评估点,PHQ-9分数突然增加,这与三个秋季队列的新学年开始相对应。相比之下,三个春季队列没有表现出类似的变化。研究2表明,对于所有三个秋季队列(n = 522),0.60分的变化是显著的(95%CI 0.42-0.78;p 结论:虽然研究结果没有表明国有企业的任何显著影响,但它们强调了新冠肺炎期间新学年对大学生心理健康的影响。试验注册UMIN,CTR-00031307。注册日期:2018年2月14日。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Dynamics of depressive states among university students in Japan during the COVID-19 pandemic: an interrupted time series analysis.

Dynamics of depressive states among university students in Japan during the COVID-19 pandemic: an interrupted time series analysis.

Dynamics of depressive states among university students in Japan during the COVID-19 pandemic: an interrupted time series analysis.

Background: The coronavirus disease 2019 (COVID-19) pandemic was reported to have increased depression among university students which was associated with impairments in their campus lives. This study examined changes in depressive states among Japanese university students during the COVID-19 pandemic.

Methods: A secondary data analysis from a factorial randomized controlled trial involving smartphone-based cognitive-behavioral therapy was performed. Six cohorts (N = 1626) underwent an 8-week intervention during the spring or autumn of 2019-2021, with a 9-month follow-up. We evaluated participants' depressive states weekly using the Patient Health Questionnaire-9 (PHQ-9) during the intervention, with monthly evaluations thereafter. The follow-up periods included Japan's four states of emergency (SOEs) to control COVID-19. Hypothesizing that SOEs caused a sudden worsening of depressive states, Study 1 compared the cohorts' PHQ-9 scores, and Study 2 employed time series analysis with a mixed-effects model to estimate identified changes in PHQ-9 scores.

Results: Although no changes in depressive states were observed in relation to the SOEs, Study 1 identified sudden increases in PHQ-9 scores at the 28-week evaluation point, which corresponded to the beginning of the new academic year for the three autumn cohorts. In contrast, the three spring cohorts did not exhibit similar changes. Study 2 showed that, for all three autumn cohorts (n = 522), the 0.60-point change was significant (95% CI 0.42-0.78; p < .001) at 28 weeks; that is, when their timeline was interrupted.

Conclusions: While the results do not indicate any notable impact of the SOEs, they highlight the influence of the new academic year on university students' mental health during COVID-19. Trial registration UMIN, CTR-000031307. Registered on February 14, 2018.

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来源期刊
CiteScore
6.60
自引率
2.70%
发文量
43
审稿时长
>12 weeks
期刊介绍: Annals of General Psychiatry considers manuscripts on all aspects of psychiatry, including neuroscience and psychological medicine. Both basic and clinical neuroscience contributions are encouraged. Annals of General Psychiatry emphasizes a biopsychosocial approach to illness and health and strongly supports and follows the principles of evidence-based medicine. As an open access journal, Annals of General Psychiatry facilitates the worldwide distribution of high quality psychiatry and mental health research. The journal considers submissions on a wide range of topics including, but not limited to, psychopharmacology, forensic psychiatry, psychotic disorders, psychiatric genetics, and mood and anxiety disorders.
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