药物相关的颌骨坏死:放射科医生的作用。

R. Alemán Millares, E. Santos Armentia, S. Del Campo Estepar, M. Novoa Ferro
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引用次数: 0

摘要

近几十年来,双磷酸盐的可怕副作用,颌骨坏死,已经被广泛报道和详细描述。颌骨的骨坏死包括由于这些抗再吸收药物导致的部分上颌骨的破坏。近年来,市场上出现了同样会导致颌骨坏死的新药(例如,一些单克隆抗体或抗血管生成药物)。因此,术语“双磷酸盐相关颌骨坏死”已被“药物相关颌骨坏死(MRONJ)”所取代。本综述旨在描述MRONJ的放射学特征,尽管这些特征是非特异性的,但放射科医生需要在适当的临床背景下认识到。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Medication-related osteonecrosis of the jaw: the radiologist’s role

In recent decades, the dreaded adverse effect of bisphosphonates, osteonecrosis of the jaw, has been widely reported and described in detail. Osteonecrosis of the jaw consists of the destruction of part of the maxilla as a consequence of these antiresorptive drugs. In recent years, new drugs that can also cause osteonecrosis of the jaw (e.g., some monoclonal antibodies or antiangiogenic drugs) have come on the market. For this reason, the term “bisphosphonate-related osteonecrosis of the jaw” has been replaced with “medication-related osteonecrosis of the jaw (MRONJ).

This review aims to describe the radiologic characteristics of MRONJ that, although nonspecific, radiologists need to recognize in the appropriate clinical context.

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