杯盘比增大且眼压正常的早产儿杯盘比的纵向变化。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-02-01 Epub Date: 2024-01-16 DOI:10.1080/08820538.2023.2264381

Tae Hwan Kim, Yoon Hyung Kwon, Myo Jing Kim, Sang Wook Jin

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引用次数: 0

摘要

目的：评价杯盘比（CDR）在伴有增大和眼压正常的早产儿中的纵向变化。婴儿被分为扩大CDR组和对照组。分析了人口统计学数据、胎龄（GA）、出生体重（BW）、垂直杯盘比（vCDR）、眼压和角膜直径。结果：283例患者中，扩增CDR组38例（13.4%），对照组245例（86.6%）。在扩大CDR组中，vCDR和基线IOP为0.63 ± 0.12和12.7 ± 2.2 mmHg。在对照组中，vCDR和基线IOP为0.18 ± 0.05和10.9 ± 1.7 mmHg。GA为40时的IOP 第1周和第2周年龄明显低于基线时的年龄。vCDR在基线和每次随访之间的差异并不显著。vCDR与GA和BW呈负相关；然而，这些相关性并不显著。结论：vCDR在2岁之前没有显著变化 CDR增大且眼压正常的早产儿的年龄。然而，需要密切随访，直到其他可靠的青光眼检查，如光学相干断层扫描和视野，成为可能。

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Longitudinal Change of Cup to Disc Ratio in Premature Infants with Enlarged Cup to Disc Ratio and Normal Intraocular Pressure.

Purpose: To evaluate the longitudinal change of cup to disc ratio (CDR) in premature infants with enlarged CDR and normal intraocular pressure (IOP).

Methods: This retrospective, observational study included 283 eyes of 283 premature infants at single center. Infants were divided into enlarged CDR and control groups. Data on demographics, gestational age (GA), birth weight (BW), vertical cup to disc ratio (vCDR), IOP, and corneal diameter were analyzed.

Results: Of the 283 patients, 38 (13.4%) and 245 (86.6%) were in the enlarged CDR and control groups, respectively. In the enlarged CDR group, the vCDR and baseline IOP was 0.63 ± 0.12 and 12.7 ± 2.2 mmHg, respectively. In the control group, the vCDR and baseline IOP was 0.18 ± 0.05 and 10.9 ± 1.7 mmHg, respectively. The IOP at a GA of 40 weeks and at 1 and 2 years of age were significantly lower than that at baseline. The differences in vCDR between baseline and each follow-up visit were not significant. vCDR was negatively correlated with GA and BW; however, these correlations were not significant.

Conclusions: The vCDR did not significantly change up to age of 2 years of age in premature infants with enlarged CDR and normal IOP. However, close follow-up is needed until other reliable glaucoma examinations, such as optical coherence tomography and visual fields, can be possible.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.