基于适体的病毒检测在动物中的应用。

W Zhang, L Xiao, J Luo, M Wu, Y Zhu, F Cong
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引用次数: 0

摘要

病毒感染是动物疾病的常见原因,越来越多地需要适当的方法来检测动物体内的病毒病原体。在这方面,类似于抗原-抗体的相互作用,适体对其各自的靶分子具有高亲和力和特异性,并且可以使用外显子富集配体的系统进化(SELEX)技术进行选择。最近,在开发用于病毒检测的适体选择和基于适体的传感器方面取得了重大进展,在此我们回顾了基于适体检测动物病毒感染的一些最新进展。这篇综述将作为病毒诊断中基于适体的策略的综合资源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of aptamer-based viral detection in animals.

Viral infections are common causes of diseases in animals and appropriate methods are increasingly being required to detect viral pathogens in animals. In this regard, similar to antigen- -antibody interactions, aptamers have high affinity and specificity for their respective target molecules, and can be selected using the Systematic Evolution of Ligands by EXponential enrichment (SELEX) technique. Recently, significant progress has been made in the development of aptamer selection and aptamer-based sensors for viral detection, and here we review some of the recent advances in aptamer-based detection of viral infections in animals. This review will serve as a comprehensive resource for aptamer-based strategies in viral diagnostics.

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