成人患者的广泛性淋巴异常:一项卓越的放射学诊断。

J. Sainz Sánchez , A. Aranaz Murillo , E. Andrés Villares , J. García Maroto
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引用次数: 0

摘要

广泛性淋巴异常(GLA)是一种罕见的先天性疾病,继发于除中枢神经系统外的任何器官的淋巴管增殖。GLA有广泛的临床和放射学表现,其中溶骨性病变最为广泛,肋骨是最常见的受累骨。GLA主要诊断于儿童和年轻人;然而,在极少数情况下,它可以保持无症状,并在老年患者中偶然发现。我们报告了一例不寻常的GLA病例,发生在一名无症状的54岁男子身上,他在CT上有非典型分布的纯囊性骨病变;测量这些病变的Hounsfield(HU)使我们能够怀疑GLA。MRI、PET/CT、CT引导的细针穿刺活检和荧光镜引导的经皮椎体活检证实了这一怀疑。手术切除其中一个病灶后,组织学研究提供了明确的诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Generalized lymphatic anomaly in adult patients: An eminently radiological diagnosis

Generalized lymphatic anomaly (GLA) is an uncommon congenital disease secondary to the proliferation of lymphatic vessels in any organ except the central nervous system. GLA has a wide spectrum of clinical and radiological presentations, among which osteolytic lesions are the most widespread, being the ribs the most commonly affected bone. GLA is diagnosed mainly in children and young adults; nevertheless, on rare occasions it can remain asymptomatic and be detected incidentally in older patients. We present an unusual case of GLA in an asymptomatic 54-year-old man who had atypically distributed, purely cystic bone lesions on CT; measuring the Hounsfield (HU) of these lesions enabled us to suspect GLA. This suspicion was confirmed with MRI, PET/CT, CT-guided fine-needle aspiration biopsy, and fluoroscopy-guided percutaneous vertebral biopsy. After surgical resection of one of the lesions, histologic study provided the definitive diagnosis.

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