极低和极低出生体重早产儿拔管成功的预测因素。

0 CRITICAL CARE MEDICINE
Canadian Journal of Respiratory Therapy Pub Date : 2023-09-15 eCollection Date: 2023-01-01 DOI:10.29390/001c.87789
Nilson Willamy Bastos de Souza Júnior, Tathiane Ribeiro Rosa, Jane Cecília Kreling Cerântola, Ligia Silvana Lopes Ferrari, Vanessa Suziane Probst, Josiane Marques Felcar
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引用次数: 0

摘要

背景:尽管有创机械通气(IMV)有助于极低出生体重早产儿(ELBW)的存活,但长期使用也会导致临床结果不理想。本研究旨在确定极低出生体重(VLBW)和极低出生重量(ELBW)早产儿拔管成功的决定性因素。方法:队列研究纳入了孕龄早产儿(GA)。结果:纳入83名早产儿。GA和拔管后动脉二氧化碳分压(PaCO2)可预测拔管成功率。FG的婴儿GA和BW较低,而SG的婴儿在拔管时体重较高,拔管后PaCO2较低;它还涉及在计划事件之后的指定时间段(72小时)内发生的所有方面。结论:GA和拔管后PaCO2是极低体重和极低体重早产儿拔管成功的预测因素。经历拔管失败的婴儿在拔管前出生体重较低,FiO2较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Predictive factors for extubation success in very low and extremely low birth weight preterm infants.

Predictive factors for extubation success in very low and extremely low birth weight preterm infants.

Background: Although invasive mechanical ventilation (IMV) has contributed to the survival of preterm infants with extremely low birth weight (ELBW), it is also associated with unsatisfactory clinical outcomes when used for prolonged periods. This study aimed to identify factors that may be decisive for extubation success in very low birth weight (VLBW) and extremely low birth weight (ELBW) preterm infants.

Methods: The cohort study included preterm infants with gestational age (GA) <36 weeks, birth weight (BW) <1500 grams who underwent IMV, born between 2015 and 2018. The infants were allocated into two groups: extubation success (SG) or failure (FG). A stepwise logistic regression model was created to determine variables associated with successful extubation.

Results: Eighty-three preterm infants were included. GA and post-extubation arterial partial pressure of carbon dioxide (PaCO2) were predictive of extubation success. Infants from FG had lower GA and BW, while those from SG had higher weight at extubation and lower post-extubation PaCO2.

Discussion: Although we found post-extubation PaCO2 as an extubation success predictor, which is a variable representative of the moment after the primary outcome, this does not diminish its clinical relevance since extubation does not implicate in ET removal only; it also involves all the aspects that take place within a specified period (72 hours) after the planned event.

Conclusion: GA and post-extubation PaCO2 were predictors for extubation success in VLBW and ELBW preterm infants. Infants who experienced extubation failure had lower birth weight and higher FiO2 prior to extubation.

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来源期刊
Canadian Journal of Respiratory Therapy
Canadian Journal of Respiratory Therapy Health Professions-Health Professions (miscellaneous)
CiteScore
2.00
自引率
0.00%
发文量
34
期刊介绍: The CJRT is published four times a year and represents the interests of respiratory therapists nationally and internationally. The CJRT has been redesigned to act as an educational dissemination tool. The CJRT encourages submission of original articles, papers, commentaries, case studies, literature reviews and directed reading papers. Submissions can be sent to Rita Hansen.
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