重症监护病房患者艰难梭菌的基因组流行病学。

IF 58.7 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Medicine Pub Date : 2023-10-02 DOI:10.1038/s41591-023-02550-x

引用次数: 0

摘要

从密集采样的重症监护病房（ICU）人群中对艰难梭菌进行的全基因组测序显示，这些患者中有许多人携带毒性艰难梭菌。这种携带并不会导致高水平的交叉传播，但却与临床上明显的艰难梭菌感染风险大大增加有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Genomic epidemiology of Clostridioides difficile in individuals admitted to an intensive care unit

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Genomic epidemiology of Clostridioides difficile in individuals admitted to an intensive care unit

Whole-genome sequencing of Clostridioides difficile from a densely sampled intensive care unit (ICU) population showed that many of these patients harbor toxigenic C. difficile. This carriage did not lead to high levels of cross-transmission but was associated with a greatly increased risk of developing clinically overt C. difficile infection.

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来源期刊

Nature Medicine 医学-生化与分子生物学

CiteScore

100.90

自引率

0.70%

发文量

525

审稿时长

1 months

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